Lower back pain continues to be a global epidemic, limiting quality of life and ability to work,
due in large part to symptomatic disc degeneration. Development of more effective and less …

Objective This study aims to tackle the existing challenges associated with the prediction
and optimization of pharmaceutical interventions for osteoarthritis (OA). The primary …

Cells respond to mechanical stimuli, and microfluidic devices are used to create highly
controlled environments for cellular mechanobiology studies. Previously, we developed a …

Microfluidic devices are used to apply mechanical stimuli, such as compressive force and
flow shear force, to cells for mechanobiology studies. Previously, we developed a …

Mechanical forces acting on cells have been recognized as an important aspect of cells'
environment because cells adjust their cellular functions in response to such forces …

Microfluidic devices manipulate fluids at the micro-or sub-millimeter scale and are used for
various applications. Courses on microfluidics offer students an opportunity to learn about …

Diabetic neuropathy is a prevalent complication of diabetes mellitus and is characterized by
progressive nerve damage that results in sensory and motor deficits. Although traditional in …

Microfluidic lab-on-a-chip (LoC) technology has driven numerous innovations due to their
ability to perform laboratory-scale experiments on a single chip using microchannels …

Previously, we used photolithography and soft lithography to make a microfluidic cell
compression device with a thin layer of polydimethylsiloxane (PDMS) for use with …

Lower back pain is the leading cause of physical disability worldwide. In the United States,
annual costs associated with lower back pain exceed $100 billion, as 70%-80% of …