Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
The mechanisms of nanoparticle delivery to solid tumours
Nanoparticles for the detection and treatment of cancer have suffered from limited clinical
translation. A key problem has been the lack of understanding of the mechanisms of …
translation. A key problem has been the lack of understanding of the mechanisms of …
The exit of nanoparticles from solid tumours
Nanoparticles enter tumours through endothelial cells, gaps or other mechanisms, but how
they exit is unclear. The current paradigm states that collapsed tumour lymphatic vessels …
they exit is unclear. The current paradigm states that collapsed tumour lymphatic vessels …
[HTML][HTML] Recent advances and clinical translation of liposomal delivery systems in cancer therapy
J Chen, S Hu, M Sun, J Shi, H Zhang, H Yu… - European Journal of …, 2024 - Elsevier
The limitations of conventional cancer treatment are driving the emergence and
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …
[HTML][HTML] Nanocarrier-based targeted therapies for myocardial infarction
Myocardial infarction is a major cause of morbidity and mortality worldwide. Due to poor
inherent regeneration of the adult mammalian myocardium and challenges with effective …
inherent regeneration of the adult mammalian myocardium and challenges with effective …
Emerging targeted therapeutic strategies for the treatment of triple-negative breast cancer
L Kumari, L Mishra, P Patel, N Sharma… - Journal of Drug …, 2023 - Taylor & Francis
Triple-negative breast cancer (TNBC), a subtype of breast cancer that lacks expression of
oestrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …
oestrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …
Evaluation of Efficiency of Liposome-Entrapped Iridium (III) Complexes Inhibiting Tumor Growth In Vitro and In Vivo
H Hu, J Chen, F Zhang, Z Sheng, Y Yang… - Journal of Medicinal …, 2024 - ACS Publications
In this paper, three new iridium (III) complexes:[Ir (piq) 2 (DFIPP)] PF6 (piq= deprotonated 1-
phenylisoquinoline, DFIPP= 3, 4-difluoro-2-(1 H-imidazo [4, 5-f][1, 10] phenenthrolin-2-yl) …
phenylisoquinoline, DFIPP= 3, 4-difluoro-2-(1 H-imidazo [4, 5-f][1, 10] phenenthrolin-2-yl) …
Engineering of Amphiphilic Erlotinib Analogue as Novel Nanomedicine for Non-Small Cell Lung Cancer Therapy
M Cong, H Pang, G Xie, F Li, C Li, H Sun… - International Journal …, 2023 - Taylor & Francis
Purpose Molecular targeted therapy is one of the most pivotal strategies in the treatment of
non-small cell lung cancer, yet its curative effect is severely compromised by the poor …
non-small cell lung cancer, yet its curative effect is severely compromised by the poor …
A low-cost, flexible extruder for liposomes synthesis and application for Murrayafoline A delivery for cancer treatment
DT Pham, LP Nguyen, QTH Pham… - Journal of …, 2022 - journals.sagepub.com
Liposomal encapsulation is a drug delivery strategy with many advantages, such as
improved bioavailability, ability to carry large drug loads, as well as controllability and …
improved bioavailability, ability to carry large drug loads, as well as controllability and …
Nano-Drug Carriers for Chemotherapeutic Agents Delivery in Cancer Disease Treatment
Cancer is a leading cause of mortality in the non-communicable disease category.
Researchers are on a constant quest to identify novel drug targets as well as therapeutic …
Researchers are on a constant quest to identify novel drug targets as well as therapeutic …