Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …

S Kansız, YM Elçin - Advances in Colloid and Interface Science, 2023 - Elsevier
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …

The mechanisms of nanoparticle delivery to solid tumours

LNM Nguyen, W Ngo, ZP Lin, S Sindhwani… - Nature Reviews …, 2024 - nature.com
Nanoparticles for the detection and treatment of cancer have suffered from limited clinical
translation. A key problem has been the lack of understanding of the mechanisms of …

The exit of nanoparticles from solid tumours

LNM Nguyen, ZP Lin, S Sindhwani, P MacMillan… - Nature Materials, 2023 - nature.com
Nanoparticles enter tumours through endothelial cells, gaps or other mechanisms, but how
they exit is unclear. The current paradigm states that collapsed tumour lymphatic vessels …

[HTML][HTML] Recent advances and clinical translation of liposomal delivery systems in cancer therapy

J Chen, S Hu, M Sun, J Shi, H Zhang, H Yu… - European Journal of …, 2024 - Elsevier
The limitations of conventional cancer treatment are driving the emergence and
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …

[HTML][HTML] Nanocarrier-based targeted therapies for myocardial infarction

TA George, CC Hsu, A Meeson, DJ Lundy - Pharmaceutics, 2022 - mdpi.com
Myocardial infarction is a major cause of morbidity and mortality worldwide. Due to poor
inherent regeneration of the adult mammalian myocardium and challenges with effective …

Emerging targeted therapeutic strategies for the treatment of triple-negative breast cancer

L Kumari, L Mishra, P Patel, N Sharma… - Journal of Drug …, 2023 - Taylor & Francis
Triple-negative breast cancer (TNBC), a subtype of breast cancer that lacks expression of
oestrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …

Evaluation of Efficiency of Liposome-Entrapped Iridium (III) Complexes Inhibiting Tumor Growth In Vitro and In Vivo

H Hu, J Chen, F Zhang, Z Sheng, Y Yang… - Journal of Medicinal …, 2024 - ACS Publications
In this paper, three new iridium (III) complexes:[Ir (piq) 2 (DFIPP)] PF6 (piq= deprotonated 1-
phenylisoquinoline, DFIPP= 3, 4-difluoro-2-(1 H-imidazo [4, 5-f][1, 10] phenenthrolin-2-yl) …

Engineering of Amphiphilic Erlotinib Analogue as Novel Nanomedicine for Non-Small Cell Lung Cancer Therapy

M Cong, H Pang, G Xie, F Li, C Li, H Sun… - International Journal …, 2023 - Taylor & Francis
Purpose Molecular targeted therapy is one of the most pivotal strategies in the treatment of
non-small cell lung cancer, yet its curative effect is severely compromised by the poor …

A low-cost, flexible extruder for liposomes synthesis and application for Murrayafoline A delivery for cancer treatment

DT Pham, LP Nguyen, QTH Pham… - Journal of …, 2022 - journals.sagepub.com
Liposomal encapsulation is a drug delivery strategy with many advantages, such as
improved bioavailability, ability to carry large drug loads, as well as controllability and …

Nano-Drug Carriers for Chemotherapeutic Agents Delivery in Cancer Disease Treatment

P Ahlawat, R Kumar, A Kumar, PK Gupta - Nano Drug Delivery for Cancer …, 2024 - Springer
Cancer is a leading cause of mortality in the non-communicable disease category.
Researchers are on a constant quest to identify novel drug targets as well as therapeutic …