Heart failure with preserved ejection fraction: JACC scientific statement

BA Borlaug, K Sharma, SJ Shah, JE Ho - Journal of the American College …, 2023 - Elsevier
The incidence and prevalence of heart failure with preserved ejection fraction (HFpEF)
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …

Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets

BA Borlaug, MD Jensen, DW Kitzman… - Cardiovascular …, 2022 - academic.oup.com
Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Impact of epicardial adipose tissue on cardiovascular haemodynamics, metabolic profile, and prognosis in heart failure

NR Pugliese, F Paneni, M Mazzola… - European journal of …, 2021 - Wiley Online Library
Aims We evaluated the impact of echocardiographic epicardial adipose tissue (EAT) on
cardiovascular haemodynamics, metabolic profile and prognosis in heart failure (HF) using …

Heart failure with preserved ejection fraction: mechanisms and treatment strategies

K Omote, FH Verbrugge… - Annual review of medicine, 2022 - annualreviews.org
Approximately half of all patients with heart failure (HF) have a preserved ejection fraction,
and the prevalence is growing rapidly given the aging population in many countries and the …

Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review

A Pandey, SJ Shah, J Butler, DL Kellogg Jr… - Journal of the American …, 2021 - jacc.org
Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved
ejection fraction (HFpEF), the most common form of heart failure among older individuals …

Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy–A clinical consensus statement of the …

M Guazzi, M Wilhelm, M Halle… - European journal of …, 2022 - Wiley Online Library
Patients with heart failure with preserved ejection fraction (HFpEF) universally complain of
exercise intolerance and dyspnoea as key clinical correlates. Cardiac as well as …

Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions

NR Pugliese, P Pellicori, F Filidei… - Cardiovascular …, 2022 - academic.oup.com
Many patients with symptoms and signs of heart failure have a left ventricular ejection
fraction≥ 50%, termed heart failure with preserved ejection fraction (HFpEF). HFpEF is a …

Role of epicardial adipose tissue in cardiovascular diseases: a review

M Konwerski, A Gąsecka, G Opolski, M Grabowski… - Biology, 2022 - mdpi.com
Simple Summary Cardiovascular diseases (CVDs) are the leading causes of death
worldwide. Epicardial adipose tissue (EAT) is one of the most important risk factors for …

Pericardial fat and the risk of heart failure

S Kenchaiah, J Ding, JJ Carr, MA Allison… - Journal of the American …, 2021 - jacc.org
Background Obesity is a well-established risk factor for heart failure (HF). However,
implications of pericardial fat on incident HF is unclear. Objectives This study sought to …

Obesity and cardiovascular disease: an ESC clinical consensus statement

KC Koskinas, EM Van Craenenbroeck… - European Heart …, 2024 - academic.oup.com
The global prevalence of obesity has more than doubled over the past four decades,
currently affecting more than a billion individuals. Beyond its recognition as a high-risk …