Hepatitis C virus (HCV) is a worldwide health problem. No vaccine is available against this
pathogen and therapeutic treatments currently in use are of limited efficacy. In the present …

Hepatitis C virus (HCV) infection is a major worldwide problem. Chronic hepatitis C is
recognized as one of the major causes of cirrhosis, hepatocellular carcinoma, and liver …

The eradication of hepatitis C virus (HCV) infection is a public health priority. Despite the
efficiency of treatment with direct-acting antivirals, the high cost of the therapy and the lack of …

Little is known about the mechanism of hepatitis C virion assembly. So the capacity of the
entire Hepatitis C virus core protein (HCcAg) produced in Pichia pastoris to form particles …

Development of heterologous systems to produce useful HCV vaccine candidates is an
important part of HCV research. In this study different HCV structural region variants were …

Plasmids expressing variants of the hepatitis C virus (HCV) core, E1 and E2 proteins
individually or as polyproteins were administered to BALB/c mice. All plasmids induced a …

The in vitro self-assembly properties of the entire hepatitis C virus core protein (HCcAg)
obtained from Pichia pastoris cells and the induction of specific antibody immune response …

In the present study, recombinant HCV (hepatitis C virus) core proteins enhanced the
immune response elicited by a co‐delivered DNA vaccine encoding HCV core and …

HCV (hepatitis C virus) infection is among the leading causes of chronic liver disease, but
currently there is no vaccine available. Data have accumulated about the importance of …

HCV is a worldwide health problem despite the recent advances in the development of more
effective therapies. No preventive vaccine is available against this pathogen. However, non …