Objective This meta-review aimed to present all available quantitative pooled estimates for
the associations between psychosocial work exposures and health outcomes using a …

The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

Cardiovascular disease remains the leading cause of disease burden globally, which
underlies the continuing need to identify new complementary targets for prevention. Over the …

Background The influence of social relationships on morbidity is widely accepted, but the
size of the risk to cardiovascular health is unclear. Objective We undertook a systematic …

The role of psychosocial work stress as a risk factor for chronic disease has been the subject
of considerable debate. Many researchers argue in support of a causal connection while …

Background Long working hours might increase the risk of cardiovascular disease, but
prospective evidence is scarce, imprecise, and mostly limited to coronary heart disease. We …

Objective To examine whether physical inactivity is a risk factor for dementia, with attention
to the role of cardiometabolic disease in this association and reverse causation bias that …

Numerous risk factors for mental disorders have been identified. However, we do not know
how many disorders we could prevent and to what extent by modifying these risk factors …

Epidemiological studies have shown that a substantial proportion of acute coronary events
occur in individuals who lack the traditional high-risk cardiovascular (CV) profile. Mental …

Aims Epidemiological studies indicate that traffic noise increases the incidence of coronary
artery disease, hypertension and stroke. The underlying mechanisms remain largely …