Oxidative stress in autism spectrum disorder—current progress of mechanisms and biomarkers
X Liu, J Lin, H Zhang, NU Khan, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder that has been
diagnosed in an increasing number of children around the world. Existing data suggest that …
diagnosed in an increasing number of children around the world. Existing data suggest that …
Glutathione synthesis
SC Lu - Biochimica et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
BACKGROUND: Glutathione (GSH) is present in all mammalian tissues as the most
abundant non-protein thiol that defends against oxidative stress. GSH is also a key …
abundant non-protein thiol that defends against oxidative stress. GSH is also a key …
Metabolomics reveal nanoplastic-induced mitochondrial damage in human liver and lung cells
Plastic debris in the global biosphere is an increasing concern, and nanoplastic (NPs)
toxicity in humans is far from being understood. Studies have indicated that NPs can affect …
toxicity in humans is far from being understood. Studies have indicated that NPs can affect …
Ethanol metabolism in the liver, the induction of oxidant stress, and the antioxidant defense system
ML Contreras-Zentella, D Villalobos-García… - Antioxidants, 2022 - mdpi.com
The liver metabolizes ethanol through three enzymatic pathways: alcohol dehydrogenase
(ADH), cytochrome p450 (also called MEOS), and catalase. Alcohol dehydrogenase class I …
(ADH), cytochrome p450 (also called MEOS), and catalase. Alcohol dehydrogenase class I …
[HTML][HTML] Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation
CA Labarrere, GS Kassab - Frontiers in Nutrition, 2022 - frontiersin.org
Many local and systemic diseases especially diseases that are leading causes of death
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …
Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis
DA Rossignol, RE Frye - Molecular psychiatry, 2012 - nature.com
A comprehensive literature search was performed to collate evidence of mitochondrial
dysfunction in autism spectrum disorders (ASDs) with two primary objectives. First, features …
dysfunction in autism spectrum disorders (ASDs) with two primary objectives. First, features …
Regulation of glutathione synthesis
SC Lu - Molecular aspects of medicine, 2009 - Elsevier
Glutathione (GSH) is a ubiquitous intracellular peptide with diverse functions that include
detoxification, antioxidant defense, maintenance of thiol status, and modulation of cell …
detoxification, antioxidant defense, maintenance of thiol status, and modulation of cell …
Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism
DA Rossignol, RE Frye - Frontiers in physiology, 2014 - frontiersin.org
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
disorders that are defined solely on the basis of behavioral observations. Therefore, ASD …
disorders that are defined solely on the basis of behavioral observations. Therefore, ASD …
Glutathione in cancer biology and therapy
JM Estrela, A Ortega, E Obrador - Critical reviews in clinical …, 2006 - Taylor & Francis
The glutathione (GSH) content of cancer cells is particularly relevant in regulating mutagenic
mechanisms, DNA synthesis, growth, and multidrug and radiation resistance. In malignant …
mechanisms, DNA synthesis, growth, and multidrug and radiation resistance. In malignant …
Crosstalk between neuroinflammation and oxidative stress in epilepsy
T Fabisiak, M Patel - Frontiers in cell and developmental biology, 2022 - frontiersin.org
The roles of both neuroinflammation and oxidative stress in the pathophysiology of epilepsy
have begun to receive considerable attention in recent years. However, these concepts are …
have begun to receive considerable attention in recent years. However, these concepts are …