Controlling vector-borne diseases by releasing modified mosquitoes

HA Flores, SL O'Neill - Nature Reviews Microbiology, 2018 - nature.com
Aedes mosquito-transmitted diseases, such as dengue, Zika and chikungunya, are
becoming major global health emergencies while old threats, such as yellow fever, are re …

[HTML][HTML] West Nile virus: an update on pathobiology, epidemiology, diagnostics, control and “one health” implications

G Habarugira, WW Suen, J Hobson-Peters, RA Hall… - Pathogens, 2020 - mdpi.com
West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe,
lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its …

Vector biology meets disease control: using basic research to fight vector-borne diseases

WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

[HTML][HTML] Development of a confinable gene drive system in the human disease vector Aedes aegypti

M Li, T Yang, NP Kandul, M Bui, S Gamez, R Raban… - Elife, 2020 - elifesciences.org
Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …

Evolutionary Ecology of Wolbachia Releases for Disease Control

PA Ross, M Turelli, AA Hoffmann - Annual review of genetics, 2019 - annualreviews.org
Wolbachia is an endosymbiotic Alphaproteobacteria that can suppress insect-borne
diseases through decreasing host virus transmission (population replacement) or through …

Control methods against invasive Aedes mosquitoes in Europe: a review

F Baldacchino, B Caputo, F Chandre… - Pest management …, 2015 - Wiley Online Library
Five species of invasive Aedes mosquitoes have recently become established in Europe:
Ae. albopictus, Ae. aegypti, Ae. japonicus japonicus, Ae. koreicus and Ae. atropalpus. These …

Mosquito microbiota and implications for disease control

H Gao, C Cui, L Wang, M Jacobs-Lorena, S Wang - Trends in parasitology, 2020 - cell.com
Mosquito-transmitted diseases account for about 500 000 deaths every year. Blocking these
pathogens in the mosquito vector before they are transmitted to humans is an effective …

[HTML][HTML] Paratransgenesis: a promising new strategy for mosquito vector control

ABB Wilke, MT Marrelli - Parasites & vectors, 2015 - Springer
The three main mosquito genera, Anopheles, Aedes and Culex, transmit respectively
malaria, dengue and lymphatic filariasis. Current mosquito control strategies have proved …

[HTML][HTML] Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains

J Martinez, B Longdon, S Bauer, YS Chan… - PLoS …, 2014 - journals.plos.org
In the last decade, bacterial symbionts have been shown to play an important role in
protecting hosts against pathogens. Wolbachia, a widespread symbiont in arthropods, can …

The microbiome modulates arbovirus transmission in mosquitoes

S Hegde, JL Rasgon, GL Hughes - Current opinion in virology, 2015 - Elsevier
Highlights•Complex interactions occur within the mosquito holobiome that profoundly alter
the phenotype of the host.•Bacteria can enhance or suppress arbovirus transmission in …