While the processing of mRNA is essential for gene expression, recent findings have
highlighted that RNA processing is systematically altered in cancer. Mutations in RNA …

The cellular signaling network involves co-ordinated regulation of numerous signaling
molecules that aid the maintenance of cellular as well as organismal homeostasis. Aberrant …

Background: Long noncoding RNAs (lncRNAs) are important regulators of biological
processes involved in vascular tissue homeostasis and disease development. The present …

Background Bone metastasis is the leading cause of tumor‐related death in prostate cancer
(PCa) patients. Long noncoding RNAs (lncRNAs) have been well documented to be …

The functions of the proto-oncoprotein c-Myc and the tumor suppressor p53 in controlling
cell survival and proliferation are inextricably linked as “Yin and Yang” partners in normal …

Noncoding RNAs are functional transcripts that are not translated into proteins. They
represent the largest portion of the human transcriptome and have been shown to regulate …

Abstract DNA: DNA: RNA triplexes that are formed through Hoogsteen base-pairing of the
RNA in the major groove of the DNA duplex have been observed in vitro, but the extent to …

Genomic amplification of the distal portion of chromosome 3q, which encodes a number of
oncogenic proteins, is one of the most frequent chromosomal abnormalities in malignancy …

Long non-coding RNAs (lncRNAs) impact cell function via numerous mechanisms. In the
nucleus, interactions between lncRNAs and DNA and the consequent formation of non …

Osteoporosis is a common systemic skeletal disorder resulting in bone fragility and
increased fracture risk. It is still necessary to explore its detailed mechanisms and identify …