Horizontal gene transfer and adaptive evolution in bacteria

BJ Arnold, IT Huang, WP Hanage - Nature Reviews Microbiology, 2022 - nature.com
Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …

Examining horizontal gene transfer in microbial communities

IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …

Metagenome-assembled genome binning methods with short reads disproportionately fail for plasmids and genomic islands

F Maguire, B Jia, KL Gray, WYV Lau… - Microbial …, 2020 - microbiologyresearch.org
Metagenomic methods enable the simultaneous characterization of microbial communities
without time-consuming and bias-inducing culturing. Metagenome-assembled genome …

Typing methods based on whole genome sequencing data

L Uelze, J Grützke, M Borowiak, JA Hammerl… - One Health …, 2020 - Springer
Whole genome sequencing (WGS) of foodborne pathogens has become an effective
method for investigating the information contained in the genome sequence of bacterial …

Enabling genomic island prediction and comparison in multiple genomes to investigate bacterial evolution and outbreaks

C Bertelli, KL Gray, N Woods, AC Lim… - Microbial …, 2022 - microbiologyresearch.org
Outbreaks of virulent and/or drug-resistant bacteria have a significant impact on human
health and major economic consequences. Genomic islands (GIs; defined as clusters of …

Pan-Genome Plasticity and Virulence Factors: A Natural Treasure Trove for Acinetobacter baumannii

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2024 - mdpi.com
Acinetobacter baumannii is a Gram-negative pathogen responsible for a variety of
community-and hospital-acquired infections. It is recognized as a life-threatening pathogen …

Comparative Genomic Analysis of Antarctic Pseudomonas Isolates with 2,4,6-Trinitrotoluene Transformation Capabilities Reveals Their Unique Features for …

MÁ Cabrera, SL Márquez, JM Pérez-Donoso - Genes, 2022 - mdpi.com
The nitroaromatic explosive 2, 4, 6-trinitrotoluene (TNT) is a highly toxic and persistent
environmental pollutant. Since physicochemical methods for remediation are poorly …

The notable achievements and the prospects of bacterial pathogen genomics

GD Amoutzias, M Nikolaidis, A Hesketh - Microorganisms, 2022 - mdpi.com
Throughout the entirety of human history, bacterial pathogens have played an important role
and even shaped the fate of civilizations. The application of genomics within the last 27 …

Leveraging comparative genomics to uncover alien genes in bacterial genomes

S Sengupta, RK Azad - Microbial Genomics, 2023 - microbiologyresearch.org
A significant challenge in bacterial genomics is to catalogue genes acquired through the
evolutionary process of horizontal gene transfer (HGT). Both comparative genomics and …