Measurements methods for the development of MicroRNA-based tests for cancer diagnosis

F Precazzini, S Detassis, AS Imperatori… - International journal of …, 2021 - mdpi.com
Studies investigating microRNAs as potential biomarkers for cancer, immune-related
diseases, or cardiac pathogenic diseases, among others, have exponentially increased in …

Small non-coding RNAs in human cancer

Q Xiong, Y Zhang, J Li, Q Zhu - Genes, 2022 - mdpi.com
Small non-coding RNAs are widespread in the biological world and have been extensively
explored over the past decades. Their fundamental roles in human health and disease are …

MiR-130b/TNF-α/NF-κB/VEGFA loop inhibits prostate cancer angiogenesis

HQ Mu, YH He, SB Wang, S Yang, YJ Wang… - Clinical and …, 2020 - Springer
Background Angiogenesis is a critical biological process essential for solid cancer growth
and metastasis. It has been shown that microRNAs (miRNAs) play a vital role in a variety of …

microRNAs make the call in cancer personalized medicine

S Detassis, M Grasso, V Del Vescovo… - Frontiers in cell and …, 2017 - frontiersin.org
Since their discovery and the advent of RNA interference, microRNAs have drawn enormous
attention because of their ubiquitous involvement in cellular pathways from life to death, from …

MiRNA-671-5p Promotes prostate cancer development and metastasis by targeting NFIA/CRYAB axis

Z Zhu, L Luo, Q Xiang, J Wang, Y Liu, Y Deng… - Cell Death & …, 2020 - nature.com
Prostate cancer (PCa) is the second cause of death due to malignancy among men, and
metastasis is the leading cause of mortality in patients with PCa. MicroRNAs (miRNAs) play …

Cluster miRNAs and cancer: Diagnostic, prognostic and therapeutic opportunities

SP Kabekkodu, V Shukla, VK Varghese… - Wiley …, 2020 - Wiley Online Library
MiRNAs are class of noncoding RNA important for gene expression regulation in many
plants, animals and viruses. MiRNA clusters contain a set of two or more miRNA encoding …

Epigenetic regulation of MicroRNA clusters and families during tumor development

J Gregorova, P Vychytilova-Faltejskova, S Sevcikova - Cancers, 2021 - mdpi.com
Simple Summary In this review, the history of RNA interference discovery and current
knowledge about microRNA biogenesis and post-transcriptional regulation of gene …

MicroRNA-30a-5pme: a novel diagnostic and prognostic biomarker for clear cell renal cell carcinoma in tissue and urine samples

G Outeiro-Pinho, D Barros-Silva, E Aznar… - Journal of Experimental …, 2020 - Springer
Background The rising incidence of renal cell carcinomas (RCC) constitutes a significant
challenge owing to risk of overtreatment. Because aberrant microRNA (miR) promoter …

16p11. 2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

JG Roth, KL Muench, A Asokan, VM Mallett, H Gai… - Elife, 2020 - elifesciences.org
Microdeletions and microduplications of the 16p11. 2 chromosomal locus are associated
with syndromic neurodevelopmental disorders and reciprocal physiological conditions such …

Overexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer

Q Li, Z Li, S Wei, W Wang, Z Chen, L Zhang… - Journal of experimental …, 2017 - Springer
Background MicroRNAs are endogenously expressed, small non-coding RNAs that
modulate gene expression by targeting specific mRNAs, resulting in translational repression …