Heat shock proteins (Hsps) are overexpressed in a wide range of human cancers and are
implicated in tumor cell proliferation, differentiation, invasion, metastasis, death, and …

Simple Summary Skin cancers (SC) are a frequent type of malignancy in white populations
and include malignant melanoma and non-melanoma skin cancer. Due to their increasing …

Calorie restriction extends lifespan in a broad range of organisms, from yeasts to mammals.
Numerous hypotheses have been proposed to explain this phenomenon, including …

The formation of complexes between proteins and ligands is fundamental to biological
processes at the molecular level. Manipulation of molecular recognition between ligands …

Of all of the epithelial ovarian cancers, clear cell carcinoma (CCC) of the ovary has the worst
prognosis. We applied the oligonucleotide array technique to identify genes generally …

Peripheral T cell lymphoma, unspecified (PTCL/U), the most common form of PTCL, displays
heterogeneous morphology and phenotype, poor response to treatment, and poor …

Abstract Nicotinamide N-methyltransferase (NNMT, EC 2.1. 1.1.) plays an important role in
the growth of many different tumours and is also involved in various non-neoplastic …

Glioblastoma, the most aggressive primary brain tumor in humans, exhibits a large degree of
molecular heterogeneity. Understanding the molecular pathology of a tumor and its linkage …

When it was first proposed that the budding yeast Saccharomyces cerevisiae might serve as
a model for human aging in 1959, the suggestion was met with considerable skepticism …

Abstract Heat shock protein 27 (Hsp27) is a cytoprotective chaperone that is
phosphoactivated during cell stress that prevents aggregation and/or regulate activity and …