Staphylococcus aureus, a ubiquitous pathogen, is the most common bacteria involved in
purulent acute bacterial skin and skin structure infections (ABSSSI) 1. Over the years …

Introduction Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA)
infections represent a leading cause of purulent skin and soft tissue infections in some …

Twelve different soil types that represent the soil compartments of the Czech Republic were
fortified with three antibiotics (clindamycin (CLI), sulfamethoxazole (SUL), and trimethoprim …

Introduction The use of adjunctive antibiotics directed against exotoxin production in
Staphylococcus aureus bacteremia (SAB) is widespread, and is recommended in many …

Eighteen hot topics regarding the diagnosis and management of skin and soft-tissue
infections (SSTIs) were selected and reviewed by members of the SSTI Working Group of …

Background Combination antibiotic therapy with an antitoxin agent, such as clindamycin, is
included in some guidelines for severe, toxin-mediated Staphylococcus aureus infections …

Protein synthesis inhibitor antibiotics inhibit synthesis of new proteins, including exotoxins
and other important virulence determinants in Staphylococcus aureus. A summary of the …

6. Hall RG II, Payne KD, Bain AM, et al. Multicenter evaluation of vancomycin dosing:
emphasis on obesity. Am J Med 2008; 121: 515–8. 7. Li J, Udy AA, Kirkpatrick CM, Lipman J …

Abstract Severe, invasive Streptococcus pyogenes (Strep A) infections result in greater than
500,000 deaths annually. First line treatment for such infections is benzylpenicillin, often with …

Abstract Background/Objectives Optimal management of staphylococcal scalded skin
syndrome (SSSS) has not been established. Clindamycin may benefit patients via inhibition …