Zinc complexes with nitrogen donor ligands as anticancer agents
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …
First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity
D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …
[HTML][HTML] Synthesis and characterization of different complexes derived from Schiff base and evaluation as a potential anticancer, antimicrobial, and insecticide agent
LM Aroua, SK Alhag, LA Al-Shuraym… - Saudi Journal of …, 2023 - Elsevier
The condensation of (1H-benzimidazole-2-yl) methanamine, with 2-hydroxy
naphthaldehyde lead to Schiff base ligand (H2L)(1). This was later reacted with metal salts …
naphthaldehyde lead to Schiff base ligand (H2L)(1). This was later reacted with metal salts …
Metal Complexes in cancer treatment: Journey so far
A Kumar Singh, A Kumar, H Singh… - Chemistry & …, 2023 - Wiley Online Library
Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …
High cytotoxicity of vanadium (IV) complexes with 1, 10-phenanthroline and related ligands is due to decomposition in cell culture medium
Cytotoxic effects of Metvan (cis-[V IV O (OSO 3)(Me 2 phen) 2], where Me 2 phen= 4, 7-
dimethyl-1, 10-phenanthroline) and its analogues with 1, 10-phenanthroline (phen) and 2 …
dimethyl-1, 10-phenanthroline) and its analogues with 1, 10-phenanthroline (phen) and 2 …
Cytotoxic and antimicrobial potential of benzimidazole derivatives
H Küçükbay, M Uçkun, E Apohan… - Archiv der …, 2021 - Wiley Online Library
New benzimidazole derivatives were synthesized and their structures were characterized by
spectroscopic and microanalysis techniques. The cytotoxic properties of ten benzimidazole …
spectroscopic and microanalysis techniques. The cytotoxic properties of ten benzimidazole …
Synthesis and anticancer properties of novel hydrazone derivatives incorporating pyridine and isatin moieties
Nine novel hydrazone derivatives (4a–i) incorporating pyridine and isatin moieties were
synthesized through one‐pot, four‐component heterocyclic condensation reactions. The …
synthesized through one‐pot, four‐component heterocyclic condensation reactions. The …
Synthesis and In Vitro Anticancer Evaluation of Some Benzimidazolium Salts
Colon and breast cancers were two of the four major cancers by age and sex group in
America for 2016 [1]. The number of deaths from colon cancer is higher than that from breast …
America for 2016 [1]. The number of deaths from colon cancer is higher than that from breast …
Synthesis, biological evaluation, substitution behaviour and DFT study of Pd (II) complexes incorporating benzimidazole derivative
I Mitra, S Mukherjee, B Misini, P Das… - New Journal of …, 2018 - pubs.rsc.org
To achieve potent yet specific antitum agents, a series of palladium (II) complexes (C1–C6)
employing the carrier ligand 2-aminomethylbenzimidazole with DNA intercalating property …
employing the carrier ligand 2-aminomethylbenzimidazole with DNA intercalating property …
Synthesis and evaluation of anticancer properties of novel benzimidazole ligand and their cobalt (II) and zinc (II) complexes against cancer cell lines A-2780 and DU …
Eighteen new cobalt (II) or zinc (II) complexes of benzimidazole bearing 1-benzyl and 2-
phenyl moieties were synthesized from the reaction of appropriate benzimidazole ligands …
phenyl moieties were synthesized from the reaction of appropriate benzimidazole ligands …