Zinc complexes with nitrogen donor ligands as anticancer agents

M Porchia, M Pellei, F Del Bello, C Santini - Molecules, 2020 - mdpi.com
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity

D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

[HTML][HTML] Synthesis and characterization of different complexes derived from Schiff base and evaluation as a potential anticancer, antimicrobial, and insecticide agent

LM Aroua, SK Alhag, LA Al-Shuraym… - Saudi Journal of …, 2023 - Elsevier
The condensation of (1H-benzimidazole-2-yl) methanamine, with 2-hydroxy
naphthaldehyde lead to Schiff base ligand (H2L)(1). This was later reacted with metal salts …

Metal Complexes in cancer treatment: Journey so far

A Kumar Singh, A Kumar, H Singh… - Chemistry & …, 2023 - Wiley Online Library
Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …

High cytotoxicity of vanadium (IV) complexes with 1, 10-phenanthroline and related ligands is due to decomposition in cell culture medium

M Le, O Rathje, A Levina, PA Lay - JBIC Journal of Biological Inorganic …, 2017 - Springer
Cytotoxic effects of Metvan (cis-[V IV O (OSO 3)(Me 2 phen) 2], where Me 2 phen= 4, 7-
dimethyl-1, 10-phenanthroline) and its analogues with 1, 10-phenanthroline (phen) and 2 …

Cytotoxic and antimicrobial potential of benzimidazole derivatives

H Küçükbay, M Uçkun, E Apohan… - Archiv der …, 2021 - Wiley Online Library
New benzimidazole derivatives were synthesized and their structures were characterized by
spectroscopic and microanalysis techniques. The cytotoxic properties of ten benzimidazole …

Synthesis and anticancer properties of novel hydrazone derivatives incorporating pyridine and isatin moieties

Z Zebbiche, S Tekin, H Küçükbay, F Yüksel… - Archiv Der …, 2021 - Wiley Online Library
Nine novel hydrazone derivatives (4a–i) incorporating pyridine and isatin moieties were
synthesized through one‐pot, four‐component heterocyclic condensation reactions. The …

Synthesis and In Vitro Anticancer Evaluation of Some Benzimidazolium Salts

S Akkoc, V Kayser, İÖ İlhan - Journal of Heterocyclic Chemistry, 2019 - Wiley Online Library
Colon and breast cancers were two of the four major cancers by age and sex group in
America for 2016 [1]. The number of deaths from colon cancer is higher than that from breast …

Synthesis, biological evaluation, substitution behaviour and DFT study of Pd (II) complexes incorporating benzimidazole derivative

I Mitra, S Mukherjee, B Misini, P Das… - New Journal of …, 2018 - pubs.rsc.org
To achieve potent yet specific antitum agents, a series of palladium (II) complexes (C1–C6)
employing the carrier ligand 2-aminomethylbenzimidazole with DNA intercalating property …

Synthesis and evaluation of anticancer properties of novel benzimidazole ligand and their cobalt (II) and zinc (II) complexes against cancer cell lines A-2780 and DU …

Ü Yılmaz, S Tekin, N Buğday, K Yavuz… - Inorganica Chimica …, 2019 - Elsevier
Eighteen new cobalt (II) or zinc (II) complexes of benzimidazole bearing 1-benzyl and 2-
phenyl moieties were synthesized from the reaction of appropriate benzimidazole ligands …