Organoids are established through in vitro 3D culture, and they can mimic the structure and
physiological functions of organs or tissues in vivo. Organoids have attracted much attention …

Peritoneal metastasis is the leading cause of death for gastrointestinal cancers. The native
and therapy-induced ascites ecosystems are not fully understood. Here, we characterize …

Organoids are stem cell-derived, self-organizing, 3D structures. Compared to the
conventional 2D cell culture method, 3D cultured organoids contain a variety of cell types …

BACKGROUND Three-dimensional organoid culture systems have been established as a
robust tool for elucidating mechanisms and performing drug efficacy testing. The use of …

Aging is a risk factor for cancers in various organs. Recent advances in the organoid
culturing system have made it viable to investigate the influence of aging utilizing these mini …

腹膜转移是胃癌最常见的转移形式之一, 也是临床诊治的难点. 当前, 胃癌腹膜转移的治疗仍以
全身系统化疗为主. 对于经过筛选的患者, 肿瘤细胞减灭术, 腹腔热灌注化疗和新辅助腹腔内联合 …

Organoids are three-dimensional structures derived from primary tissue or tumors that
closely mimic the architecture, histology, and function of the parental tissue. In recent years …

Most gastric cancers arise in the setting of chronic inflammation which alters gland
organization, such that acid-pumping parietal cells are lost, and remaining cells undergo …

Gastric cancer (GC) presents a significant health challenge and ranks as the fifth most
common cancer in the world. Unfortunately, most patients with GC exhaust standard care …

Organoids are in vitro 3D models that are generated using stem cells to study organ
development and regeneration. Despite the extensive research on lung organoids, there is …