Conjugates of tetrapyrrolic macrocycles as potential anticancer target-oriented photosensitizers

AM Korolchuk, VA Zolottsev, AY Misharin - Topics in Current Chemistry, 2023 - Springer
Photodynamic therapy is a minimally invasive treatment of tumors using photosensitizers,
light, and reactive oxygen species, which can destroy cellular structures. With the …

Natural chlorins as a promising platform for creating targeted theranostics in oncology

MA Grin, NV Suvorov, AF Mironov - Mendeleev Communications, 2020 - Elsevier
This review deals with the progress in the chemistry of natural chlorins and the prospects of
using their derivatives as theranostics. Particular attention is paid to the creation of targeted …

Synthesis and Preclinical Evaluation of Small-Molecule Prostate-Specific Membrane Antigen-Targeted Abiraterone Conjugate

AE Machulkin, EA Nimenko, NU Zyk, AA Uspenskaia… - Molecules, 2022 - mdpi.com
Prostate cancer is the second most common type of cancer among men. The main method of
its treatment is androgen deprivation therapy, which has a wide range of side effects. One of …

Photodynamic therapy of melanoma b16 with chlorin E6 conjugated with a PSMA-ligand

OB Abramova, MA Kaplan, MA Grin… - Bulletin of Experimental …, 2021 - Springer
The efficacy of a new photosensitizer of chlorin E6 conjugated with a prostate-specific
membrane antigen (PSMA) in photodynamic therapy of murine melanoma B16 was studied …

On the Pathomorphological Pattern of the Efficiency of Photodynamic Therapy of Murine Melanoma B16 Using a New Photosensitizer Based on Chlorin e6 Conjugate …

OB Abramova, GA Demyashkin, VV Drozhzhina… - Molecules, 2022 - mdpi.com
Photodynamic therapy (PDT) is an effective treatment for a number of solid malignancies. In
this work, the antitumor efficacy of photodynamic therapy for murine B16 melanoma with …

The First Selenoanhydride in the Series of Chlorophyll a Derivatives, Its Stability and Photoinduced Cytotoxicity

V Pogorilyy, A Plyutinskaya, N Suvorov, E Diachkova… - Molecules, 2021 - mdpi.com
In this work, we obtained the first selenium-containing chlorin with a chalcogen atom in
exlocycle E. It was shown that the spectral properties were preserved in the target …

Potential agents for combined photodynamic and chemotherapy in oncology based on Pt (II) complexes and pyridine-containing natural chlorins

M Grin, P Ostroverkhov, N Suvorov… - Journal of Porphyrins …, 2023 - World Scientific
Combined therapy is currently a popular method for increasing the efficiency of antitumor
treatment. It involves the use of two different tumor treatment methods, namely …

[HTML][HTML] Макрогетероциклические соединения-ключевое звено в создании новых функциональных материалов и молекулярных устройств

OИ Койфман, TA Aгеева, ИП Белецкая… - …, 2020 - journals.isuct.ru
Аннотация В обзоре рассмотрены последние достижения в области направленного
синтеза и применения макрогетероциклических соединений в науке, технике и …

Intramolecular cyclization of 15-carboxy-13-amide derivatives of chlorin e6 under the action of 2-Chloro-1-methylpyridinium iodide

MV Mal'shakova, DV Belykh - Journal of Porphyrins and …, 2022 - World Scientific
We have shown the possibility of intramolecular cyclization with the participation of the
carboxyl group at position 15 of the chlorin macrocycle with a primary or secondary amide …

TARGETED PHOTOSENSITIZERS WITH PHOTOINDUCED ANTITUMOR ACTIVITY BASED ON NATURAL CHLORINS

MA Grin, NV Suvorov, VA Pogorilyy, SI Tikhonov… - 2021 - elibrary.ru
TARGETED PHOTOSENSITIZERS WITH PHOTOINDUCED ANTITUMOR ACTIVITY BASED
ON NATURAL CHLORINS КОРЗИНА ПОИСК НАВИГАТОР СЕССИЯ КОНТАКТЫ …