Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most
clinical settings. Cancer is a systemic disease that induces many functional and …

Monocytes in peripheral blood circulation are the precursor of essential cells that control
tumor progression, that include tumor-associated macrophages (TAMs), dendritic cells …

Purpose: Ewing sarcoma and osteosarcoma are primary bone sarcomas occurring most
commonly in adolescents. Metastatic and relapsed disease are associated with dismal …

Purpose: Immune checkpoint inhibitors (ICI) have revolutionized the treatment of non–small
cell lung cancer (NSCLC), but predictive biomarkers of their efficacy are imperfect. The …

Circulating monocytes are a major source of tumor-associated macrophages (TAMs). TAMs
in human breast cancer (BC) support primary tumor growth and metastasis. Neoadjuvant …

Cancer treatment remains a significant challenge for the medical community, and improved
therapies are necessary to treat cancer and its associated complications. Current anticancer …

Purpose: The predictive significance of the Naples prognostic score (NPS) in HER2-positive
breast cancer is unclear. Hence we sought to evaluate the relationship between NPS and …

Hypothalamic inflammation often coincides with cancer and cachexia-anorexia. Prior work
established the significance of tumor-derived inflammatory factors in triggering hypothalamic …

Purpose: The IMpassion130 trial demonstrated the efficacy of adding atezolizumab to
paclitaxel for advanced or metastatic triple-negative breast cancer (TNBC). The current study …

Background Monocytes comprise subsets of classical, intermediate and non-classical
monocytes with distinct anti-or pro-tumor effects in breast cancer (BC). They are modulated …