[HTML][HTML] The intricate relationship between type 2 diabetes mellitus (T2DM), insulin resistance (IR), and nonalcoholic fatty liver disease (NAFLD)

DM Tanase, EM Gosav, CF Costea… - Journal of diabetes …, 2020 - hindawi.com
Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) remain as one
of the most global problematic metabolic diseases with rapidly increasing prevalence and …

Fructose impairs fat oxidation: Implications for the mechanism of western diet-induced NAFLD

MK Inci, SH Park, RN Helsley, SL Attia… - The Journal of Nutritional …, 2023 - Elsevier
Increased fructose intake from sugar-sweetened beverages and highly processed sweets is
a well-recognized risk factor for the development of obesity and its complications. Fructose …

miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling

H Sendi, I Mead, M Wan, M Mehrab-Mohseni, K Koch… - PloS one, 2018 - journals.plos.org
To investigate the role of miR-122 in the development and regression of non-alcoholic fatty
liver disease (NAFLD) in vitro, we used multicellular 3D human liver organoids developed in …

Simvastatin improves microcirculatory function in nonalcoholic fatty liver disease and downregulates oxidative and ALE-RAGE stress

ENGS Pereira, BP Araujo, KL Rodrigues, RR Silvares… - Nutrients, 2022 - mdpi.com
Increased reactive oxidative stress, lipid peroxidation, inflammation, and fibrosis, which
contribute to tissue damage and development and progression of nonalcoholic liver disease …

[HTML][HTML] Circulating fatty acid-binding protein 1 (FABP1) and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus

YC Lu, CC Chang, CP Wang, WC Hung… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
Background: Fatty acid-binding protein 1 (FABP1)(also known as liver-type fatty acid-binding
protein or LFABP) is a protein that is mainly expressed in the liver, and is associated with …

Biomarkers for early detection of acute kidney injury

MS Rizvi, KB Kashani - The Journal of Applied Laboratory …, 2017 - academic.oup.com
Background Acute kidney injury (AKI) is common in hospitalized patients and is associated
with increased morbidity, mortality, and cost. Currently, AKI is diagnosed after symptoms …

Metabolism and antioxidation regulation of total flavanones from Sedum sarmentosum Bunge against high-fat diet-induced fatty liver disease in Nile tilapia …

K Yu, K Huang, Z Tang, X Huang, L Sun… - Fish Physiology and …, 2021 - Springer
Diet-induced fatty liver is a considerable threaten to fish aquaculture due to the popularity of
the high-fat diet (HFD) feeding. Our study aims to investigate the effects of flavanones from …

Xyloketal B reverses nutritional hepatic steatosis, steatohepatitis, and liver fibrosis through activation of the PPARα/PGC1α signaling pathway

Y Tong, W Zhu, T Wen, Z Mukhamejanova… - Journal of Natural …, 2022 - ACS Publications
Nonalcoholic fatty liver disease (NAFLD) represents a class of disorders including hepatic
steatosis, steatohepatitis, and liver fibrosis. Previous research suggested that xyloketal B …

The role of elevated liver-type fatty acid-binding proteins in liver diseases

A Eguchi, M Iwasa - Pharmaceutical Research, 2021 - Springer
Liver-type fatty acid–binding protein (L-FABP) is mainly expressed in the liver as well as the
proximal tubular epithelial cells in the kidney. In general, the proteins and enzymes existing …

Mechanism Analysis of Metabolic Fatty Liver on Largemouth Bass (Micropterus salmoides) Based on Integrated Lipidomics and Proteomics

M Xue, T Yao, M Xue, F Francis, Y Qin, M Jia, J Li, X Gu - Metabolites, 2022 - mdpi.com
Metabolic fatty liver disease caused by high-starch diet restricted the intensive and
sustainable development of carnivorous fish such as largemouth bass. In this study, the …