Patients with COVID-19: in the dark-NETs of neutrophils

M Ackermann, HJ Anders, R Bilyy, GL Bowlin… - Cell Death & …, 2021 - nature.com
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …

A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics

V Mutua, LJ Gershwin - Clinical reviews in allergy & immunology, 2021 - Springer
Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

[HTML][HTML] Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer

Y Zhang, V Chandra, E Riquelme Sanchez… - Journal of experimental …, 2020 - rupress.org
Disclosure: Dr. Maitra reports Thrive Earlier Detection has licensed an invention from Johns
Hopkins University in which Dr. Maitra is listed as an inventor. The focus of the license is on …

DAMPs and NETs in sepsis

NL Denning, M Aziz, SD Gurien, P Wang - Frontiers in immunology, 2019 - frontiersin.org
Sepsis is a deadly inflammatory syndrome caused by an exaggerated immune response to
infection. Much has been focused on host response to pathogens mediated through the …

[HTML][HTML] Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19

C Radermecker, N Detrembleur, J Guiot… - Journal of Experimental …, 2020 - rupress.org
Infection with SARS-CoV-2 is causing a deadly and pandemic disease called coronavirus
disease–19 (COVID-19). While SARS-CoV-2–triggered hyperinflammatory tissue-damaging …

Neutrophil extracellular traps (NETs) take the central stage in driving autoimmune responses

E Fousert, R Toes, J Desai - Cells, 2020 - mdpi.com
Following fifteen years of research, neutrophil extracellular traps (NETs) are widely reported
in a large range of inflammatory infectious and non-infectious diseases. Cumulating …

Neutrophil extracellular traps in breast cancer and beyond: current perspectives on NET stimuli, thrombosis and metastasis, and clinical utility for diagnosis and …

HT Snoderly, BA Boone, MF Bennewitz - Breast Cancer Research, 2019 - Springer
The formation of neutrophil extracellular traps (NETs), known as NETosis, was first observed
as a novel immune response to bacterial infection, but has since been found to occur …

Extracellular HMGB1: a therapeutic target in severe pulmonary inflammation including COVID-19?

U Andersson, W Ottestad, KJ Tracey - Molecular Medicine, 2020 - Springer
Background The 2019 novel coronavirus disease (COVID-19) causes for unresolved
reasons acute respiratory distress syndrome in vulnerable individuals. There is a need to …

The emerging role of neutrophil extracellular traps in respiratory disease

SH Twaddell, KJ Baines, C Grainge, PG Gibson - Chest, 2019 - Elsevier
Neutrophil extracellular traps (NETs) are extrusions of intracellular DNA and attached
granular material that enable bacterial killing. NETs are increasingly recognized for their role …

SARS-CoV-2 infection in acute pancreatitis increases disease severity and 30-day mortality: COVID PAN collaborative study

S Pandanaboyana, J Moir, JS Leeds, K Oppong… - Gut, 2021 - gut.bmj.com
Objective There is emerging evidence that the pancreas may be a target organ of SARS-
CoV-2 infection. This aim of this study was to investigate the outcome of patients with acute …