Autosomal recessive CARD9 deficiency underlies life-threatening, invasive fungal infections
in otherwise healthy individuals normally resistant to other infectious agents. In less than 10 …

Candida species, including C. albicans in particular, can cause superficial or invasive
disease, often in patients with known acquired immunodeficiencies or iatrogenic conditions …

The C-type lectin receptor–Syk (spleen tyrosine kinase) adaptor CARD9 facilitates protective
antifungal immunity within the central nervous system (CNS), as human deficiency in …

Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal
yeasts that predominantly cause disease in immunocompromised individuals, and are …

The CARD-BCL10-MALT1 (CBM) complex is critical for the proper assembly of human
immune responses. The clinical and immunological consequences of deficiencies in some …

CARD9 is a cytosolic adaptor in myeloid cells, has a critical role in inflammatory disorders,
and provides a protective function against microbial pathogen, especially fungal infection …

Exophiala dermatitidis, a dematiaceous fungus typically found in decaying organic matter
worldwide, is a rare cause of fungal infections. Cerebral phaeohyphomycosis is a sporadic …

Purpose Caspase-associated recruitment domain-9 (CARD9) deficiency is an inborn error of
immunity that typically predisposes otherwise healthy patients to single fungal infections and …

Deficiency of caspase recruitment domain-containing protein 9 (CARD9) is an autosomal
recessive primary immunodeficiency disorder, which typically predisposes …

Purpose Persistent human papillomavirus infection (PHPVI) causes cutaneous, anogenital,
and mucosal warts. Cutaneous warts include common warts, Treeman syndrome, and …