Development of the human placenta

MY Turco, A Moffett - Development, 2019 - journals.biologists.com
The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease

MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …

[HTML][HTML] Derivation of human trophoblast stem cells

H Okae, H Toh, T Sato, H Hiura, S Takahashi… - Cell stem cell, 2018 - cell.com
Trophoblast cells play an essential role in the interactions between the fetus and mother.
Mouse trophoblast stem (TS) cells have been derived and used as the best in vitro model for …

Placental development: lessons from mouse mutants

J Rossant, JC Cross - Nature Reviews Genetics, 2001 - nature.com
The placenta is the first organ to form during mammalian embryogenesis. Problems in its
formation and function underlie many aspects of early pregnancy loss and pregnancy …

Development of structures and transport functions in the mouse placenta

ED Watson, JC Cross - Physiology, 2005 - journals.physiology.org
The placenta is essential for sustaining the growth of the fetus during gestation, and defects
in its function result in fetal growth restriction or, if more severe, fetal death. Several …

The anatomy of the normal placenta

B Huppertz - Journal of clinical pathology, 2008 - jcp.bmj.com
The placenta is the fetal organ providing the interchange between mother and fetus. This
organ needs to provide its function such as transport and secretion even during its …

Aspects of human fetoplacental vasculogenesis and angiogenesis. II. Changes during normal pregnancy

P Kaufmann, TM Mayhew, DS Charnock-Jones - Placenta, 2004 - Elsevier
In this second review, we describe the main morphological events which accompany the
development of the fetoplacental vascular system throughout normal human pregnancy and …

Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies

RN Taylor, J Grimwood, RS Taylor… - American journal of …, 2003 - Elsevier
Objective: Complicated pregnancies demonstrate abnormal decidual and placental villous
vasculature. We examined maternal concentrations of vascular endothelial growth factor …

Vascular biology of the placenta

H Weiler - Endothelial Cells in Health and Disease, 2005 - taylorfrancis.com
The placenta is a gender-specific transitory organ with the sole purpose of enabling the
growth and development of the fetus. It mediates the efficient transfer and exchange of …

Control of human trophoblast function

L Lunghi, ME Ferretti, S Medici, C Biondi… - Reproductive Biology and …, 2007 - Springer
The trophoblast, ie the peripheral part of the human conceptus, exerts a crucial role in
implantation and placentation. Both processes properly occur as a consequence of an …