Microbiota regulation of viral infections through interferon signaling

NI Wirusanti, MT Baldridge, VC Harris - Trends in microbiology, 2022 - cell.com
The interferon (IFN) response is the major early innate immune response against invading
viral pathogens and is even capable of mediating sterilizing antiviral immunity without the …

Early-life gut microbiota and its connection to metabolic health in children: Perspective on ecological drivers and need for quantitative approach

C Jian, N Carpén, O Helve, WM de Vos, K Korpela… - …, 2021 - thelancet.com
The colonisation and development of the gut microbiota has been implicated in paediatric
metabolic disorders via its powerful effect on host metabolic and immune homeostasis. Here …

Immunological Pathways Triggered by Porphyromonas gingivalis and Fusobacterium nucleatum: Therapeutic Possibilities?

KQ De Andrade, CLC Almeida-da-Silva… - Mediators of …, 2019 - Wiley Online Library
Porphyromonas gingivalis (P. gingivalis) and Fusobacterium nucleatum (F. nucleatum) are
Gram‐negative anaerobic bacteria possessing several virulence factors that make them …

[PDF][PDF] Liver alkaline phosphatase: a missing link between choleresis and biliary inflammation

R Poupon - Hepatology, 2015 - Wiley Online Library
Several lines of evidence show that serum alkaline phosphatase (AP) is not only a signpost
of cholestasis but also a surrogate marker of the severity of primary biliary cirrhosis and …

The molecular mechanisms of chronic inflammation development

M Murakami, T Hirano - Frontiers in immunology, 2012 - frontiersin.org
Inflammation is critical for the development of many complex diseases and disorders
including autoimmune diseases, metabolic syndrome, neurodegenerative diseases …

The characteristics and function of bacterial lipopolysaccharides and their endotoxic potential in humans

A Gnauck, RG Lentle, MC Kruger - International reviews of …, 2016 - Taylor & Francis
Cross-talk between enteral microbiota and human host is essential for the development and
maintenance of the human gastrointestinal and systemic immune systems. The presence of …

[PDF][PDF] NLRP3 inflammasome and host protection against bacterial infection

JJ Kim, EK Jo - Journal of Korean medical science, 2013 - synapse.koreamed.org
The inflammasome is a multi-protein complex that induces maturation of inflammatory
cytokines interleukin (IL)-1β and IL-18 through activation of caspase-1. Several nucleotide …

5-hydroxymethylfurfural mitigates lipopolysaccharide-stimulated inflammation via suppression of MAPK, NF-κB and mTOR activation in RAW 264.7 cells

F Kong, BH Lee, K Wei - Molecules, 2019 - mdpi.com
5-Hydroxymethylfurfural (5-HMF) is found in many food products including honey, dried
fruits, coffee and black garlic extracts. Here, we investigated the anti-inflammatory activity of …

Redox phospholipidomics of enzymatically generated oxygenated phospholipids as specific signals of programmed cell death

VE Kagan, YY Tyurina, WY Sun, II Vlasova… - Free Radical Biology …, 2020 - Elsevier
High fidelity and effective adaptive changes of the cell and tissue metabolism to changing
environments require strict coordination of numerous biological processes. Multicellular …

Interplay of broccoli/broccoli sprout bioactives with gut microbiota in reducing inflammation in inflammatory bowel diseases

J Holman, M Hurd, PL Moses, GM Mawe… - The Journal of nutritional …, 2023 - Elsevier
Abstract Inflammatory Bowel Diseases (IBD) are chronic, reoccurring, and debilitating
conditions characterized by inflammation in the gastrointestinal tract, some of which can …