Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …

Bile acids are a large family of atypical steroids which exert their functions by binding to a
family of ubiquitous cell membrane and nuclear receptors. There are two main bile acid …

Recent studies show that the nutraceutical supplement dihydromyricetin (DHM) can alleviate
IBD in murine models by downregulating the inflammatory pathways. However, the …

Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory disorder of
the gastrointestinal tract that arises due to complex interactions between host genetic risk …

Inflammatory bowel diseases (IBD) are chronic medical disorders characterized by recurrent
gastrointestinal inflammation. While the etiology of IBD is still unknown, the pathogenesis of …

Bile acids (BAs) as cholesterol-derived molecules play an essential role in some
physiological processes such as nutrient absorption, glucose homeostasis and regulation of …

Bile acids are steroids generated at the interface of host and intestinal microbiota. While
primary bile acids are generated in the liver from cholesterol metabolism, secondary bile …

In brief Sex differences in the gut microbiome may impact multiple aspects of human health
and disease. In this study, we review the evidence for microbial sex differences in puberty …

Gut dysbiosis has been associated with inflammatory bowel disease (IBD), one of the most
common gastrointestinal diseases. The microbial communities play essential roles in host …