Sex differences in energy metabolism: natural selection, mechanisms and consequences

F Mauvais-Jarvis - Nature Reviews Nephrology, 2024 - nature.com
Metabolic homeostasis operates differently in men and women. This sex asymmetry is the
result of evolutionary adaptations that enable women to resist loss of energy stores and …

[HTML][HTML] Brown adipose tissue: function and physiological significance

B Cannon, JAN Nedergaard - Physiological reviews, 2004 - journals.physiology.org
Abstract Cannon, Barbara, and Jan Nedergaard. Brown Adipose Tissue: Function and
Physiological Significance. Physiol Rev 84: 277–359, 2004; 10.1152/physrev. 00015.2003 …

Sex and species differences in the development of diet-induced obesity and metabolic disturbances in rodents

I Maric, JP Krieger, P van der Velden, S Börchers… - Frontiers in …, 2022 - frontiersin.org
Prevalence and health consequences of obesity differ between men and women. Yet, most
preclinical studies investigating the etiology of obesity have, to date, been conducted in …

Outdoor Temperature, Age, Sex, Body Mass Index, and Diabetic Status Determine the Prevalence, Mass, and Glucose-Uptake Activity of 18F-FDG-Detected BAT in …

V Ouellet, A Routhier-Labadie… - The Journal of …, 2011 - academic.oup.com
Context: In humans, the prevalence, mass, and glucose-uptake activity of 18F-
fluorodeoxyglucose (18F-FDG)-detected brown adipose tissue (BAT), which are expectedly …

Impact of age on the relationships of brown adipose tissue with sex and adiposity in humans

C Pfannenberg, MK Werner, S Ripkens, I Stef… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Brown adipose tissue (BAT) regulates energy homeostasis and fat mass in
mammals and newborns and, most likely, in adult humans. Because BAT activity and BAT …

Sex differences in brown adipose tissue function: sex hormones, glucocorticoids, and their crosstalk

K Kaikaew, A Grefhorst, JA Visser - Frontiers in endocrinology, 2021 - frontiersin.org
Excessive fat accumulation in the body causes overweight and obesity. To date, research
has confirmed that there are two types of adipose tissue with opposing functions: lipid …

Brown adipose tissue and seasonal variation in humans

ITH Au-Yong, N Thorn, R Ganatra, AC Perkins… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Brown adipose tissue (BAT) is present in adult humans where it may be
important in the prevention of obesity, although the main factors regulating its abundance …

Sex-dependent thermogenesis, differences in mitochondrial morphology and function, and adrenergic response in brown adipose tissue

S Rodrı́guez-Cuenca, E Pujol, R Justo… - Journal of Biological …, 2002 - ASBMB
Gender-related differences in brown adipose tissue (BAT) thermogenesis of 110-day-old
rats were studied by determining the morphological and functional features of BAT. The …

Interactions between endocrine and circadian systems

AH Tsang, JL Barclay, H Oster - Journal of molecular …, 2014 - jme.bioscientifica.com
Most of the genetic variation associated with diabetes, through genome-wide association
studies, does not reside in protein-coding regions, making the identification of functional …

Sex differences in thermoregulation in mammals: Implications for energy homeostasis

C Fernández-Peña, A Reimúndez, F Viana… - Frontiers in …, 2023 - frontiersin.org
Thermal homeostasis is a fundamental process in mammals, which allows the maintenance
of a constant internal body temperature to ensure an efficient function of cells despite …