Evolution of DNA methylome diversity in eukaryotes
Cytosine DNA methylation (5mC) is a widespread base modification in eukaryotic genomes
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …
Phylogenetics is the new genetics (for most of biodiversity)
Despite substantial progress in understanding the genetic basis for differences in
morphology, physiology, and behavior, many phenotypes of interest are difficult to study with …
morphology, physiology, and behavior, many phenotypes of interest are difficult to study with …
Molecular properties of epimutation hotspots
Mistakes in the maintenance of CG methylation are a source of heritable epimutations in
plants. Multigenerational surveys indicate that the rate of these stochastic events varies …
plants. Multigenerational surveys indicate that the rate of these stochastic events varies …
Genome evolution of the psammophyte Pugionium for desert adaptation and further speciation
Q Hu, Y Ma, T Mandáková, S Shi… - Proceedings of the …, 2021 - National Acad Sciences
Deserts exert strong selection pressures on plants, but the underlying genomic drivers of
ecological adaptation and subsequent speciation remain largely unknown. Here, we …
ecological adaptation and subsequent speciation remain largely unknown. Here, we …
Nested whole-genome duplications coincide with diversification and high morphological disparity in Brassicaceae
N Walden, DA German, EM Wolf, M Kiefer… - Nature …, 2020 - nature.com
Angiosperms have become the dominant terrestrial plant group by diversifying for~ 145
million years into a broad range of environments. During the course of evolution, numerous …
million years into a broad range of environments. During the course of evolution, numerous …
Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K
Eukaryotic genes are interrupted by introns that are removed from transcribed RNAs by
splicing. Patterns of splicing complexity differ between species, but it is unclear how these …
splicing. Patterns of splicing complexity differ between species, but it is unclear how these …
Stochasticity in gene body methylation
C Goeldel, F Johannes - Current Opinion in Plant Biology, 2023 - Elsevier
Gene body methylation (gbM) is a widely conserved epigenetic feature of plant genomes.
Efforts to delineate the mechanisms by which gbM contributes to transcriptional regulation …
Efforts to delineate the mechanisms by which gbM contributes to transcriptional regulation …
Leaf shape diversity: from genetic modules to computational models
Plant leaves display considerable variation in shape. Here, we introduce key aspects of leaf
development, focusing on the morphogenetic basis of leaf shape diversity. We discuss the …
development, focusing on the morphogenetic basis of leaf shape diversity. We discuss the …
Transcription factors evolve faster than their structural gene targets in the flavonoid pigment pathway
Dissecting the relationship between gene function and substitution rates is key to
understanding genome-wide patterns of molecular evolution. Biochemical pathways provide …
understanding genome-wide patterns of molecular evolution. Biochemical pathways provide …
Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
Epialleles are meiotically heritable variations in expression states that are independent from
changes in DNA sequence. Although they are common in plant genomes, their molecular …
changes in DNA sequence. Although they are common in plant genomes, their molecular …