The skin is the largest organ of the human body and the first line of defense against
environmental hazards. Many factors, including internal factors such as natural aging and …

Over the years, advancements in the field of oncology have made remarkable strides in
enhancing the efficacy of medical care for patients with cancer. These modernizations have …

Cardiac organoids differentiated from induced pluripotent stem cells are emerging as a
promising platform for pre-clinical drug screening, assessing cardiotoxicity, and disease …

The emerging mycotoxins enniatins (ENNs) and the traditional mycotoxin deoxynivalenol
(DON) often co-contaminate various grain raw materials and foods. While the liver is their …

Over 18 million people worldwide were diagnosed with cancer in 2020, including over
150,000 people in Australia. Although improved early detection and treatment have …

Mitochondrial fission has been noted in the pathogenesis of dilated cardiomyopathy (DCM),
but the underlying specific regulatory mechanism, especially in the development of …

Mitochondria-associated endoplasmic reticulum membranes (MAMs) are formed by physical
connections of the endoplasmic reticulum and mitochondria. Over the past decades, great …

Mitochondrial dynamics have pillar roles in several diseases including cancer. Cancer cell
survival is monitored by mitochondria which impacts several cellular functions such as cell …

Abstract Drp1 (Dynamin-Related Protein 1) is a cytoplasmic GTPase protein encoded by the
DNM1L gene that influences mitochondrial dynamics by mediating mitochondrial fission …

The complete molecular mechanism underlying doxorubicin-induced cardiomyopathy
remains incompletely elucidated. In this investigation, we engineered mice with …