Current trends in flow cytometry automated data analysis software

M Cheung, JJ Campbell, L Whitby, RJ Thomas… - Cytometry Part …, 2021 - Wiley Online Library
Automated flow cytometry (FC) data analysis tools for cell population identification and
characterization are increasingly being used in academic, biotechnology, pharmaceutical …

Assessment of automated flow cytometry data analysis tools within cell and gene therapy manufacturing

M Cheung, JJ Campbell, RJ Thomas… - International Journal of …, 2022 - mdpi.com
Flow cytometry is widely used within the manufacturing of cell and gene therapies to
measure and characterise cells. Conventional manual data analysis relies heavily on …

[HTML][HTML] Forced degradation of cell-based medicinal products guided by flow imaging microscopy: Explorative studies with Jurkat cells

AD Grabarek, W Jiskoot, A Hawe… - European Journal of …, 2021 - Elsevier
Cell-based medicinal products (CBMPs) offer ground-breaking opportunities to treat
diseases with limited or no therapeutic options. However, the intrinsic complexity of CBMPs …

[HTML][HTML] GateNet: A novel neural network architecture for automated flow cytometry gating

L Fisch, M Heming, A Schulte-Mecklenbeck… - Computers in Biology …, 2024 - Elsevier
Abstract Background and Objective: Flow cytometry is a widely used technique for
identifying cell populations in patient-derived fluids, such as peripheral blood (PB) or …

MetaGate: Interactive analysis of high-dimensional cytometry data with metadata integration

EH Ask, A Tschan-Plessl, HJ Hoel, A Kolstad, H Holte… - Patterns, 2024 - cell.com
Flow cytometry is a powerful technology for high-throughput protein quantification at the
single-cell level. Technical advances have substantially increased data complexity, but …

flowSim: Near duplicate detection for flow cytometry data

S Montante, Y Chen, RR Brinkman - Cytometry Part A, 2023 - Wiley Online Library
The analysis of large amounts of data is important for the development of machine learning
(ML) models. flowSim is the first algorithm designed to visualize, detect and remove highly …

Automated lightless cytometry on a microchip with adaptive immunomagnetic manipulation

O Civelekoglu, N Wang, AKM Arifuzzman… - Biosensors and …, 2022 - Elsevier
Surface expression of cell populations are often sought as diagnostic and prognostic
biomarkers in hematology-oncology and infectious diseases, making flow cytometry an …

The Effect of Cryopreservation on T‐Cell Subsets by Flow Cytometry Automated Algorithmic Analysis and Conventional Analysis

Q Min, Q Lv, L Jiang, Q Chen, J Peng… - Journal of Clinical …, 2025 - Wiley Online Library
Background Low‐temperature cryopreservation is a common method for scientific research
and clinical sample preservation when utilizing flow cytometry. In flow cytometry data …

Assessment of protocol impact on subjectivity uncertainty when analyzing peripheral blood mononuclear cell flow cytometry data files

R Grant, K Coopman, S Silva-Gomes… - Methods and …, 2021 - mdpi.com
Measured variability of product within Cell and Gene Therapy (CGT) manufacturing arises
from numerous sources across pre-analytical to post-analytical phases of testing. Operators …

ConvexGating infers gating strategies from clusters in single cell cytometry data

VD Friedrich, K Mai, TP Hofer, E Noessner, L Bonaguro… - bioRxiv, 2024 - biorxiv.org
Manual expert gating remains common practice for the definition of specific cell populations
in the analysis of flow cytometry data. The increasing number of measured parameters per …