Physicochemical investigations of interaction of antitumor etoposide with ionic and nonionic micelles: a spectroscopic, conductivity and voltammetric study
This work aims to comprehend the physicochemical interaction of etoposide (trade name
“VP-16”) with biological membranes using biomembrane models. Surfactants, owing to their …
“VP-16”) with biological membranes using biomembrane models. Surfactants, owing to their …
EGCG maintained Nrf2-mediated redox homeostasis and minimized etoposide resistance in lung cancer cells
Lung adenocarcinomas exhibit chemoresistance mostly due to deregulation of nuclear
factor erythroid-derived 2-like 2 (Nrf2). Epigallocatechin gallate (EGCG), was investigated for …
factor erythroid-derived 2-like 2 (Nrf2). Epigallocatechin gallate (EGCG), was investigated for …
Preparation and evaluation of etoposide-loaded lipid-based nanosuspensions for high-dose treatment of lymphoma
X Yin, L Han, S Mu, W Mu, S Liang, T Wang, Y Liu… - …, 2019 - Taylor & Francis
Aim: High-dose administration of etoposide (VP16) was limited by its poor aqueous solubility
and severe systemic toxicity on lymphoma therapy. Herein, a novel VP16-loaded lipid-based …
and severe systemic toxicity on lymphoma therapy. Herein, a novel VP16-loaded lipid-based …
Slow release of etoposide from dextran conjugation shifts etoposide activity from cytotoxicity to differentiation: a promising tool for dosage control in anticancer …
M De Nicola, E Bruni, E Traversa, L Ghibelli - … Nanotechnology, Biology and …, 2017 - Elsevier
Drug conjugation, improving drug stability, solubility and body permanence, allows
achieving impressive results in tumor control. Here, we show that conjugation may provide a …
achieving impressive results in tumor control. Here, we show that conjugation may provide a …
[图书][B] Enhanced Etoposide Solubility and Anticancer Activity Using Complexation and Nanotechnology
A Alsalhi - 2021 - search.proquest.com
Etoposide is a first line treatment for different cancer types that can be used either alone or in
combination with other therapeutic agents. However, systemic toxicity, variable oral …
combination with other therapeutic agents. However, systemic toxicity, variable oral …