Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Lipids comprise a large group of chemically heterogeneous compounds. The majority have
fatty acids (FA) as part of their structure, making these compounds suitable tools to examine …

Lipid droplets are cytosolic fat storage organelles present in most eukaryotic cells. Long
regarded merely as inert fat reservoirs, they are now emerging as major regulators of …

Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to …

Glucose and fatty acids are the major sources of energy for human body. Cholesterol, the
most abundant sterol in mammals, is a key component of cell membranes although it does …

Foamy macrophages, which have prominent lipid droplets (LDs), are found in a variety of
disease states. Toll-like receptor agonists drive triacylglycerol (TG)-rich LD development in …

Hepatocytes metabolize energy-rich cytoplasmic lipid droplets (LDs) in the lysosome-
directed process of autophagy. An organelle-selective form of this process (macrolipophagy) …

Lipid metabolism is a complex biochemical process that participates in the regulation of cell
survival and death. Ferroptosis is a form of iron‐dependent regulated cell death driven by …

Lipid droplets (LDs) originate from the endoplasmic reticulum (ER) to store triacylglycerol
(TG) and cholesterol esters. The ER protein seipin was shown to localize to ER-LD contacts …

Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …