Quaternary ammonium compounds (QACs) have represented one of the most visible and
effective classes of disinfectants for nearly a century. With simple preparation, wide structural …

Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

Efficient antimicrobials are urgently needed for the treatment of bacterial biofilms due to their
resistance to traditional drugs. Photodynamic therapy (PDT) is a new strategy that has been …

Osteomyelitis caused by methicillin‐resistant Staphylococcus aureus (MRSA) biofilm
infection is difficult to eradicate and can even be life‐threatening. Given that the infection is …

Due to the inherent resistance of bacterial biofilms to antibiotics and their serious threat to
global public health, novel therapeutic agents and strategies to tackle biofilms are urgently …

Notorious bacterial biofilms are becoming severe threats to public health worldwide. As the
important component in biofilm extracellular polymeric substances (EPS), extracellular DNA …

Increasing penetration of antibacterial agents into biofilm is a promising strategy for
improvement of therapeutic effect and slowdown of the progression of antibiotic resistance …

Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

It is expected that the projected increased usage of implantable devices in medicine will
result in a natural rise in the number of infections related to these cases. Some patients are …

New approaches to target antibacterial agents toward Gram-negative bacteria are key, given
the rise of antibiotic resistance. Since the discovery of polymyxin B nonapeptide as a potent …