Associative learning and sensory neuroplasticity: how does it happen and what is it good for?

JP McGann - Learning & Memory, 2015 - learnmem.cshlp.org
Historically, the body's sensory systems have been presumed to provide the brain with raw
information about the external environment, which the brain must interpret to select a …

Modulation of olfactory signal detection in the olfactory epithelium: focus on the internal and external environment, and the emerging role of the immune system

B Bryche, C Baly, N Meunier - Cell and Tissue Research, 2021 - Springer
Detection and discrimination of odorants by the olfactory system plays a pivotal role in
animal survival. Olfactory-based behaviors must be adapted to an ever-changing …

Fear learning enhances neural responses to threat-predictive sensory stimuli

MD Kass, MC Rosenthal, J Pottackal, JP McGann - Science, 2013 - science.org
The central nervous system rapidly learns that particular stimuli predict imminent danger.
This learning is thought to involve associations between neutral and harmful stimuli in …

Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map

DF Albeanu, AC Provost, P Agarwal, ER Soucy… - Nature …, 2018 - nature.com
Inputs from olfactory sensory neuron (OSN) axons expressing the same type of odorant
receptor (OR) converge in the glomerulus of the main olfactory bulb. A key marker of mature …

Experience-dependent plasticity of gustatory insular cortex circuits and taste preferences

HC Schiff, JF Kogan, M Isaac, LA Czarnecki… - Science …, 2023 - science.org
Early experience with food influences taste preference in adulthood. How gustatory
experience influences development of taste preferences and refinement of cortical circuits …

The functional relevance of olfactory marker protein in the vertebrate olfactory system: a never-ending story

M Dibattista, D Al Koborssy, F Genovese… - Cell and tissue …, 2021 - Springer
Olfactory marker protein (OMP) was first described as a protein expressed in olfactory
receptor neurons (ORNs) in the nasal cavity. In particular, OMP, a small cytoplasmic protein …

Differences in peripheral sensory input to the olfactory bulb between male and female mice

MD Kass, LA Czarnecki, AH Moberly, JP McGann - Scientific reports, 2017 - nature.com
Female mammals generally have a superior sense of smell than males, but the biological
basis of this difference is unknown. Here, we demonstrate sexually dimorphic neural coding …

The odorant receptor-dependent role of olfactory marker protein in olfactory receptor neurons

M Dibattista, J Reisert - Journal of Neuroscience, 2016 - Soc Neuroscience
Olfactory receptor neurons (ORNs) in the nasal cavity detect and transduce odorants into
action potentials to be conveyed to the olfactory bulb. Odorants are delivered to ORNs via …

Olfactory marker protein directly buffers cAMP to avoid depolarization-induced silencing of olfactory receptor neurons

N Nakashima, K Nakashima, A Taura… - Nature …, 2020 - nature.com
Olfactory receptor neurons (ORNs) use odour-induced intracellular cAMP surge to gate
cyclic nucleotide-gated nonselective cation (CNG) channels in cilia. Prolonged exposure to …

[HTML][HTML] Genetics, molecular control and clinical relevance of habituation learning

LER Blok, M Boon, B van Reijmersdal… - Neuroscience & …, 2022 - Elsevier
Habituation is the most fundamental form of learning. As a firewall that protects our brain
from sensory overload, it is indispensable for cognitive processes. Studies in humans and …