This review presents an overview of the dynamically developing field of mass spectrometry‐
based metabolomics. Metabolomics aims at the comprehensive and quantitative analysis of …

Liquid chromatography-mass spectrometry (LC-MS) is now a routine technique with the
development of electrospray ionisation (ESI) providing a simple and robust interface. It can …

To address the challenges associated with metabolomics analyses, such as identification of
chemical structures and elimination of experimental artifacts, we developed a platform that …

BACKGROUND Novel mass spectrometric techniques such as atmospheric pressure
ionization and tandem mass spectrometry have substantially extended the spectrum of …

A library of collision-induced dissociation (CID) accurate mass spectra has been developed
for efficient use of liquid chromatography in combination with hybrid quadrupole time-of …

Metabonomics aims at the comprehensive and quantitative analysis of wide arrays of
metabolites in biological samples. It has shown particular promise in the areas of toxicology …

The metabolome is characterized by a large number of molecules exhibiting a high diversity
of chemical structures and abundances, requiring complementary analytical platforms to …

Forensic and clinical toxicological screening procedures are employing liquid
chromatography–tandem mass spectrometry (LC-MS/MS) techniques with information …

Liquid chromatography (LC) coupled to mass spectrometry (MS) or tandem mass
spectrometry (MS/MS) is a well-established and widely used technique in clinical and …

Delineating its usage in separation, purification and detection processes across a variety of
disciplines, from industry to applied research, this work discusses the principles, techniques …