The ongoing degradation of natural systems and other environmental changes has put our
society at a crossroad with respect to our future relationship with our planet. While the …

Pathogen sequencing is a transformational proposition for microbiology laboratories and
their infectious diseases, infection control, and public health partners. Healthcare systems …

Background Antimicrobial resistance (AMR) is rising at an alarming rate and complicating
the management of infectious diseases including lower respiratory tract infections (LRTI) …

Objectives Epidemiological and whole-genome sequencing analysis of an ongoing
outbreak of Streptococcus pyogenes (Group A Streptococcus) in London (United Kingdom) …

Malaria results in over 600,000 deaths annually, with the highest burden of deaths in young
children living in sub-Saharan Africa. Molecular surveillance can provide important …

Abstract Central nervous system Infections (CNSIs) is a disease characterized by complex
pathogens, rapid disease progression, high mortality rate and high disability rate. Here, we …

To elucidate the molecular mechanisms that manifest lung abnormalities during severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we performed whole …

Since the development of Sanger sequencing in 1977, sequencing technology has played a
pivotal role in molecular biology research by enabling the interpretation of biological genetic …

Background Clinical metagenomics involves the genomic sequencing of all microorganisms
in clinical samples ideally after depletion of human DNA to increase sensitivity and reduce …

Background Nanopore metagenomics has been used for infectious disease diagnosis for
bacterial pathogens. However, this technology currently lacks comprehensive performance …