Efficacy and safety of anti-inflammatory agents in treatment of psychotic disorders–A comprehensive systematic review and meta-analysis
R Jeppesen, RHB Christensen, EMJ Pedersen… - Brain, behavior, and …, 2020 - Elsevier
Objective Antipsychotic effects of immunomodulating drugs have been suggested; however,
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …
[HTML][HTML] Statins and inflammation: new therapeutic opportunities in psychiatry
SW Kim, HJ Kang, M Jhon, JW Kim, JY Lee… - Frontiers in …, 2019 - frontiersin.org
Statins, which are widely used to treat hypercholesterolemia, have anti-inflammatory and
anti-oxidant effects. These are thought to be responsible for the potential effects of statins on …
anti-oxidant effects. These are thought to be responsible for the potential effects of statins on …
Role of inflammation in the pathogenesis of schizophrenia: A review of the evidence, proposed mechanisms and implications for treatment
Aim Over the past several decades, there has been a growing research interest in the role of
inflammation in the pathogenesis of schizophrenia. This review aims to summarize evidence …
inflammation in the pathogenesis of schizophrenia. This review aims to summarize evidence …
An overview of the bioactivity of monacolin K/lovastatin
Z Xiong, X Cao, Q Wen, Z Chen, Z Cheng… - Food and chemical …, 2019 - Elsevier
Monacolin K (MK) is the principal active substance in Monascus-fermentation products (eg
red yeast rice). MK is effective in reducing cholesterol levels in humans and has been widely …
red yeast rice). MK is effective in reducing cholesterol levels in humans and has been widely …
Pharmacological management of glucose dysregulation in patients treated with second-generation antipsychotics
Fasting hyperglycemia, impaired glucose tolerance, prediabetes, and diabetes are
frequently present in patients treated with second-generation antipsychotics (SGAPs) for …
frequently present in patients treated with second-generation antipsychotics (SGAPs) for …
[HTML][HTML] Is it time for a paradigm shift in the treatment of schizophrenia? the use of inflammation-reducing and neuroprotective Drugs—A review
Comprehending the pathogenesis of schizophrenia represents a challenge for global
mental health. To date, although it is evident that alterations in dopaminergic, serotonergic …
mental health. To date, although it is evident that alterations in dopaminergic, serotonergic …
An overview on the biological activity and anti-cancer mechanism of lovastatin
L Xie, G Zhu, J Shang, X Chen, C Zhang, X Ji, Q Zhang… - Cellular …, 2021 - Elsevier
Lovastatin, a secondary metabolite isolated from fungi, is often used as a representative
drug to reduce blood lipid concentration and treat hypercholesterolemia. Its structure is …
drug to reduce blood lipid concentration and treat hypercholesterolemia. Its structure is …
[HTML][HTML] Anti-inflammatory strategies for schizophrenia: a review of evidence for therapeutic applications and drug repurposing
J Hong, M Bang - Clinical Psychopharmacology and Neuroscience, 2020 - ncbi.nlm.nih.gov
Schizophrenia is a debilitating psychiatric disorder with a substantial socioeconomic and
humanistic burden. Currently available treatment strategies mostly rely on antipsychotic …
humanistic burden. Currently available treatment strategies mostly rely on antipsychotic …
[HTML][HTML] Application of deep learning algorithm on whole genome sequencing data uncovers structural variants associated with multiple mental disorders in African …
Mental disorders present a global health concern, while the diagnosis of mental disorders
can be challenging. The diagnosis is even harder for patients who have more than one type …
can be challenging. The diagnosis is even harder for patients who have more than one type …
[HTML][HTML] Cytokine imbalance as a biomarker of treatment-resistant schizophrenia
NA Shnayder, AK Khasanova, AI Strelnik… - International Journal of …, 2022 - mdpi.com
Treatment-resistant schizophrenia (TRS) is an important and unresolved problem in
biological and clinical psychiatry. Approximately 30% of cases of schizophrenia (Sch) are …
biological and clinical psychiatry. Approximately 30% of cases of schizophrenia (Sch) are …