Epidemiology and Pathophysiology of Multiple Sclerosis : CONTINUUM: Lifelong Learning in
Neurology Account Register Activate Subscription Help Subscribe American Academy of …

Myalgic encephalomyelitis (ME) or Chronic Fatigue Syndrome (CFS) is a neglected,
debilitating multi-systemic disease without diagnostic marker or therapy. Despite evidence …

The concept that dietary changes could improve the response to cancer therapy is extremely
attractive to many patients, who are highly motivated to take control of at least some aspect …

The ketogenic diet (KD) is a high-fat low-carbohydrate diet that has been used for decades
as a non-pharmacologic approach to treat metabolic disorders and refractory pediatric …

Cholesterol is an essential component of all cell membranes and particularly enriched in
myelin membranes. Myelin membranes are a major target of immune attacks in the chronic …

Background Intermittent fasting or calorie restriction (CR) diets provide anti-inflammatory
and neuroprotective advantages in models of multiple sclerosis (MS); data in humans are …

Pro‐inflammatory signals induce metabolic reprogramming in innate and adaptive immune
cells of both myeloid and lymphoid lineage, characterized by a shift to aerobic glycolysis …

Multiple sclerosis (MS) is a multifactorial, central nervous system, immune-mediated disease
characterized by inflammation, demyelination, and neurodegeneration. Evidence suggests a …

Multiple sclerosis (MS) is an autoimmune disorder characterized by demyelination and
neurodegeneration in the central nervous system (CNS); severe symptoms lead MS patients …

To maintain homeostasis, the body, including the brain, reprograms its metabolism in
response to altered nutrition or disease. However, the consequences of these challenges for …