Decellularized xenografts in regenerative medicine: From processing to clinical application
H Capella‐Monsonís, DI Zeugolis - Xenotransplantation, 2021 - Wiley Online Library
Decellularized xenografts are an inherent component of regenerative medicine. Their
preserved structure, mechanical integrity and biofunctional composition have well …
preserved structure, mechanical integrity and biofunctional composition have well …
Evaluation of transcatheter heart valve biomaterials: Biomechanical characterization of bovine and porcine pericardium
Objective Bovine pericardium (BP) has been identified as a choice biomaterial for the
development of surgical bioprosthetic heart valves (BHV) and transcatheter aortic valves …
development of surgical bioprosthetic heart valves (BHV) and transcatheter aortic valves …
An investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves
Valvular heart diseases are complex disorders, varying in pathophysiological mechanism
and affected valve components. Understanding the effects of these diseases on valve …
and affected valve components. Understanding the effects of these diseases on valve …
Manifold learning based data-driven modeling for soft biological tissues
Data-driven modeling directly utilizes experimental data with machine learning techniques
to predict a material's response without the necessity of using phenomenological constitutive …
to predict a material's response without the necessity of using phenomenological constitutive …
Biomaterial characterization of off‐the‐shelf decellularized porcine pericardial tissue for use in prosthetic valvular applications
Fixed pericardial tissue is commonly used for commercially available xenograft valve
implants, and has proven durability, but lacks the capability to remodel and grow …
implants, and has proven durability, but lacks the capability to remodel and grow …
Biomaterials and biofabrication strategies for tissue-engineered heart valves
Current mechanical and bioprosthetic heart valve replacements suffer from thrombogenicity
or poor durability and do not grow, regenerate, or repair. Tissue-engineered heart valves …
or poor durability and do not grow, regenerate, or repair. Tissue-engineered heart valves …
Early safety and feasibility of a first-in-class biomimetic transcatheter aortic valve-DurAVR
SK Kodali, P Sorajja, CU Meduri, K Feldt… - …, 2023 - pmc.ncbi.nlm.nih.gov
Background TAVI is a widely accepted treatment for patients with severe aortic stenosis
(AS). Despite the adoption of diverse therapies, opportunities remain to develop …
(AS). Despite the adoption of diverse therapies, opportunities remain to develop …
Valve leaflet‐inspired elastomeric scaffolds with tunable and anisotropic mechanical properties
Fibrous scaffolds, which can mimic the elastic and anisotropic mechanical properties of
native tissues, hold great promise in recapitulating the native tissue microenvironment. We …
native tissues, hold great promise in recapitulating the native tissue microenvironment. We …
Ex vivo experimental characterizations for understanding the interrelationship between tissue mechanics and collagen microstructure of porcine mitral valve leaflets
Unidirectional blood flow in the left side of the heart is regulated by the mitral valve. To better
understand the mitral valve function, researchers have examined the structural and …
understand the mitral valve function, researchers have examined the structural and …
An improved parameter estimation and comparison for soft tissue constitutive models containing an exponential function
A Aggarwal - Biomechanics and Modeling in Mechanobiology, 2017 - Springer
Motivated by the well-known result that stiffness of soft tissue is proportional to the stress,
many of the constitutive laws for soft tissues contain an exponential function. In this work, we …
many of the constitutive laws for soft tissues contain an exponential function. In this work, we …