Molecular imaging can allow the non-invasive assessment of biological and biochemical
processes in living subjects. Such technologies therefore have the potential to enhance our …

Positron emission tomography (PET) is a noninvasive imaging technique that provides a
functional or metabolic assessment of normal tissue or disease conditions. Fluorine 18 …

Purpose Current standard of care conventional imaging modalities (CIM) such as X-ray
computed tomography (CT) and bone scan can be limited for detection of metastatic prostate …

Purpose: We have synthesized and evaluated in vivo 2-(3-{1-carboxy-5-[(6-[18F] fluoro-
pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid,[18F] DCFPyL, as a potential …

Purpose To compare the accuracy of 18 F-FACBC and 11 C-choline PET/CT in patients
radically treated for prostate cancer presenting with biochemical relapse. Methods This …

Prostate-specific membrane antigen (PSMA) is a type II integral membrane protein
expressed on the surface of prostate cancer (PCa) cells, particularly in androgen …

Context Radiolabelled choline positron emission tomography has changed the
management of prostate cancer patients. However, new emerging radiopharmaceutical …

Glutamate carboxypeptidase II (GCPII) is a membrane-bound binuclear zinc
metallopeptidase with the highest expression levels found in the nervous and prostatic …

Prostate cancer (PCa) is the second leading cause of cancer-related death in American
men. Positron emission tomography/computed tomography (PET/CT) with emerging …

Molecular imaging of tumor metabolism has gained considerable interest, since preclinical
studies have indicated a close relationship between the activation of various oncogenes and …