A review of high shear wet granulation for better process understanding, control and product development

B Liu, J Wang, J Zeng, L Zhao, Y Wang, Y Feng… - Powder Technology, 2021 - Elsevier
High shear wet granulation (HSWG) is considered a complicated and multivariate
pharmaceutical process that is influenced by a large number of variables derived from …

Simulation of unit operations in formulation development of tablets using computational fluid dynamics

S Hemamanjushree, VK Tippavajhala - AApS PharmSciTech, 2020 - Springer
Tablets are the most customarily used solid oral unit dosage form for its better patient
compliance. Preparation of these tablets include granulation, granule drying, die filling, and …

Detection of spark discharges in an agitated Mars dust simulant isolated from foreign surfaces

JM Harper, J Dufek, GD McDonald - Icarus, 2021 - Elsevier
Numerous laboratory experiments, starting in the Viking Lander era, have reported that
frictional interactions between Martian analog dust grains can catalyze electrostatic …

Precision forecasting of spray-dry desulfurization using Gaussian noise data augmentation and k-fold cross-validation optimized neural computing

RS Makomere, L Koech, HL Rutto… - Journal of Environmental …, 2024 - Taylor & Francis
Perceptron models have become integral tools for pattern recognition and classification
problems in engineering fields. This study envisioned implementing artificial neural …

Model development and validation of fluid bed wet granulation with dry binder addition using a population balance model methodology

SV Muddu, A Tamrakar, P Pandey, R Ramachandran - Processes, 2018 - mdpi.com
An experimental study in industry was previously carried out on a batch fluid bed granulation
system by varying the inlet fluidizing air temperature, binder liquid spray atomization …

Analysis of collision characteristics in a 3D gas-solid tapered fluidized bed

E Heidari, A Daeichian, S Movahedirad… - … Research and Design, 2022 - Elsevier
This study concerns the dynamic of particle-particle collision characteristics in a three-
dimensional gas-solid tapered fluidized bed. To this aim, a two-way coupled discrete …

复方钙制剂物性及感官评价体系的构建.

李海枝, 刘义凤, 潘聪, 于有强… - … Food Science & …, 2021 - search.ebscohost.com
为开发出一款溶解性较好, 口感易于接受的补钙产品, 本文基于对补钙产品原料的评价继而对各
种原料进行复配, 且采用流化床制粒工艺改善复方钙制剂的流动性; 最后利用电子鼻 …

Validation and Verification of Numerical Models

BH Mohammed, YK Abbas, BR Gudivaka… - … Dimensions and the …, 2024 - igi-global.com
The conceptual differences between the two expressions are extremely important for the
development of this work, since the code used, although analysed through example cases …

Particle dynamics in a pseudo-2D spouted bed: Experiments and Euler–Lagrange simulations

GGB Antunes, A Bück, FP Mariano, AG Girardi… - Chemical Engineering …, 2024 - Elsevier
This study is dedicated to a comprehensive examination of particle dynamics within a
pseudo-2D spouted bed, employing a combination of experimental analysis and numerical …

Predicting Granular Growth Processes: Model Development, Implementation and Assessment for Industrial Applications

A Tamrakar - 2019 - search.proquest.com
Growth of granular particles-whether desired or undesired-are quite common in various
industrial operations from agrochemical manufacturing to pharmaceutical product …