Mechanisms and disease consequences of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
The power of plasticity—metabolic regulation of hepatic stellate cells
Hepatic stellate cells (HSCs) are resident non-parenchymal liver pericytes whose plasticity
enables them to regulate a remarkable range of physiologic and pathologic responses. To …
enables them to regulate a remarkable range of physiologic and pathologic responses. To …
Role of liver sinusoidal endothelial cells in non-alcoholic fatty liver disease
A Hammoutene, PE Rautou - Journal of hepatology, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and its complications are an expanding health
problem associated with the metabolic syndrome. Liver sinusoidal endothelial cells (LSECs) …
problem associated with the metabolic syndrome. Liver sinusoidal endothelial cells (LSECs) …
[HTML][HTML] Cenicriviroc lacked efficacy to treat liver fibrosis in nonalcoholic steatohepatitis: AURORA phase III randomized study
Abstract Background And Aims Cenicriviroc (CVC) is a novel, orally administered,
chemokine receptor type 2 and 5 antagonist that showed antifibrotic potential in preclinical …
chemokine receptor type 2 and 5 antagonist that showed antifibrotic potential in preclinical …
Sparcl1 promotes nonalcoholic steatohepatitis progression in mice through upregulation of CCL2
Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of chronic liver disease
ranging from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH). However, the …
ranging from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH). However, the …
Exosomes-mediated tumor metastasis through reshaping tumor microenvironment and distant niche
X Luo, Y Li, Z Hua, X Xue, X Wang, M Pang… - Journal of Controlled …, 2023 - Elsevier
Tumor-derived exosomes (TDEs) are the particular communicator and messenger between
tumor cells and other cells containing cancer-associated genetic materials and proteins. And …
tumor cells and other cells containing cancer-associated genetic materials and proteins. And …
Metabolic spectrum of liver failure in type 2 diabetes and obesity: from NAFLD to NASH to HCC
H Kim, DS Lee, TH An, HJ Park, WK Kim… - International journal of …, 2021 - mdpi.com
Liver disease is the spectrum of liver damage ranging from simple steatosis called as
nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically …
nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically …
Cenicriviroc for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis: AURORA Phase 3 study design
Introduction Nonalcoholic steatohepatitis (NASH) is a sub-classification of nonalcoholic fatty
liver disease (NAFLD) characterized by increased risk of progressive liver fibrosis …
liver disease (NAFLD) characterized by increased risk of progressive liver fibrosis …
Nonalcoholic fatty liver disease: current therapies and future perspectives in drug delivery
Nonalcoholic fatty liver disease (NAFLD) affects approximately 25% of the adult population
worldwide. This pathology can progress into end-stage liver disease with life-threatening …
worldwide. This pathology can progress into end-stage liver disease with life-threatening …
A narrative review: CXC chemokines influence immune surveillance in obesity and obesity-related diseases: Type 2 diabetes and nonalcoholic fatty liver disease
Adipose tissue develops lipids, aberrant adipokines, chemokines, and pro-inflammatory
cytokines as a consequence of the low-grade systemic inflammation that characterizes …
cytokines as a consequence of the low-grade systemic inflammation that characterizes …