The ability to make decisions and act quickly without hesitation can be advantageous in
many settings. However, when persistently expressed, impulsive decisions and actions are …

A decade ago, we hypothesized that drug addiction can be viewed as a transition from
voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by …

During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Relatively little is known about the neuropathophysiology of binge-eating disorder (BED).
Here, the evidence from neuroimaging, neurocognitive, genetics, and animal studies are …

This review discusses the evidence for the hypothesis that the development of drug
addiction can be understood in terms of interactions between Pavlovian and instrumental …

Disruptions to inhibitory control are believed to contribute to multiple aspects of drug abuse,
from preexisting vulnerability in at-risk individuals, through escalation to dependence, to …

Borderline personality disorder (BPD) and attention-deficit-hyperactivity disorder (ADHD)
are both characterized by high impulsivity and difficulties in controlling anger and …

Drug addiction is widely recognized to afflict some but not all individuals by virtue of
underlying risk markers and traits involving multifaceted interactions between polygenic and …

Research on the inter-relationship between drug abuse and social stress has primarily
focused on the role of stress exposure during adulthood and more recently, adolescence …

Impulsive and aggressive behaviors are both modulated by serotonergic signaling,
specifically through the serotonin 1B receptor (5-HT1BR). 5-HT1BR knockout mice show …