Albumin, the most abundant circulating protein in blood, is an essential protein which binds
and transports various drugs and substances, maintains the oncotic pressure of blood and …

Hypoalbuminemia is associated with the acquisition and severity of infectious diseases, and
intact innate and adaptive immune responses depend on albumin. Albumin oxidation and …

The endothelial glycocalyx comprises a complex layer of membrane-bound proteoglycans,
secreted glycosaminoglycans, glycoproteins, glycolipids and bound plasma proteins such …

Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,
increasing vascular permeability, promoting activation of the coagulation cascade, tissue …

Preclinical studies in animals and human clinical trials question whether the endothelial
glycocalyx layer is a clinically important permeability barrier. Glycocalyx breakdown …

Protein‐losing enteropathy, or PLE, is not a disease but a syndrome that develops in
numerous disease states of differing etiologies and often involving the lymphatic system …

Serum albumin (ALB), one of the most important proteins in human physiology, has the main
functions of maintaining plasma oncotic pressure and plasma volume, transporting …

Evidence links the liver to development of colorectal cancer (CRC). However, it remains
unknown how liver function may influence CRC risk in the general population. We …

Introduction: Liver failure is characterized by compromised hepatic detoxification, protein
synthesis, and metabolic derangements leading to an accumulation of a broad spectrum of …

Objective Positive fluid balance is common among critically ill patients and leads to worse
outcomes, particularly in sepsis, acute respiratory distress syndrome, and acute kidney …