Parchorin, p64 and the related chloride intracellular channel (CLIC) proteins are widely
expressed in multicellular organisms and have emerged as candidates for novel, auto …

Plasma membrane channels have been extensively studied, and their physiological roles
are well established. In contrast, relatively little information is available about intracellular …

Emerging evidences demonstrate significance of chloride channels in cardiac function and
cardioprotection from ischemia–reperfusion (IR) injury. Unlike mitochondrial potassium …

Intracellular organelles are membranous structures central for maintaining cellular
physiology and the overall health of the cell. To maintain cellular function, intracellular …

Chloride channels were detergent-extracted from Torpedo electroplax plasma membrane
vesicles and reconstituted into liposomes by rapid detergent removal and a freeze …

We present evidence that the potent chloride channel blocker NPPB has protonophoric
activity in the mitochondria and across the plasma membrane of phagocytic cells. The …

Many intracellular membranes contain ion channels, although their physiological roles are
often poorly understood. In this study we incorporated single anion channels colocalized …

1. An intracellular anion channel, known to be co-localized in brain endoplsmic reticulum
membranes with ryanodine-sensitive calcium-release channels, was incorporated into …

The purification of ion channels requires the quantitative measurement of channel
abundance. We describe a simple and sensitive 36 Cl− uptake assay for quantitative …

We investigated Cl− transport pathways in the apical and basolateral membranes of rabbit
esophageal epithelial cells (EEC) using conventional and ion-selective microelectrodes …