[HTML][HTML] Neurotheranostics as personalized medicines
The discipline of neurotheranostics was forged to improve diagnostic and therapeutic
clinical outcomes for neurological disorders. Research was facilitated, in largest measure …
clinical outcomes for neurological disorders. Research was facilitated, in largest measure …
Nanotechnology in peripheral nerve repair and reconstruction
The recent progress in biomaterials science and development of tubular conduits (TCs) still
fails in solving the current challenges in the treatment of peripheral nerve injuries (PNIs), in …
fails in solving the current challenges in the treatment of peripheral nerve injuries (PNIs), in …
Nanoscale effects in dendrimer-mediated targeting of neuroinflammation
Neuroinflammation, mediated by activated microglia and astrocytes, plays a key role in the
pathogenesis of many neurological disorders. Systemically-administered dendrimers target …
pathogenesis of many neurological disorders. Systemically-administered dendrimers target …
Targeting specific cells in the brain with nanomedicines for CNS therapies
Abstract Treatment of Central Nervous System (CNS) disorders still remains a major clinical
challenge. The Blood–Brain Barrier (BBB), known as the major hindrance, greatly limits …
challenge. The Blood–Brain Barrier (BBB), known as the major hindrance, greatly limits …
Anticancer copper (II) phosphorus dendrimers are potent proapoptotic Bax activators
S Mignani, N El Brahmi, L Eloy, J Poupon… - European Journal of …, 2017 - Elsevier
A multivalent phosphorus dendrimer 1G 3 and its corresponding Cu-complex, 1G 3-Cu have
been recently identified as agents retaining high antiproliferative potency. This …
been recently identified as agents retaining high antiproliferative potency. This …
Can dendrimer based nanoparticles fight neurodegenerative diseases? Current situation versus other established approaches
S Mignani, M Bryszewska, M Zablocka… - Progress in Polymer …, 2017 - Elsevier
For several decades, the treatment of central nervous system (CNS) disorders such as, for
instance, Alzheimer's disease (AD), Huntington's disease (HD), and Parkinson's disease …
instance, Alzheimer's disease (AD), Huntington's disease (HD), and Parkinson's disease …
In vivo therapeutic applications of phosphorus dendrimers: State of the art
S Mignani, X Shi, V Ceña, D Shcharbin… - Drug Discovery …, 2021 - Elsevier
Among the different types of dendrimers, those that incorporate phosphorus in various
positions in their structures present fascinating properties and have wide applications in …
positions in their structures present fascinating properties and have wide applications in …
The blood–brain barrier and beyond: Nano-based neuropharmacology and the role of extracellular matrix
P Henrich-Noack, D Nikitovic, M Neagu… - … , Biology and Medicine, 2019 - Elsevier
Restrained drug delivery due to the blood–brain barrier (BBB) considerably limits options for
the treatment of brain pathologies. The utilization of nanoparticulate (NP) carriers has been …
the treatment of brain pathologies. The utilization of nanoparticulate (NP) carriers has been …
Treatment of refractory epilepsy patients with autologous mesenchymal stem cells reduces seizure frequency: an open label study
F Hlebokazov, T Dakukina, S Ihnatsenko… - Advances in medical …, 2017 - Elsevier
Purpose Existing anti-epileptic drugs (AED) have limited efficiency in many patients,
necessitating the search for alternative approaches such as stem cell therapy. We report the …
necessitating the search for alternative approaches such as stem cell therapy. We report the …
Dendrimers as powerful building blocks in central nervous system disease: headed for successful nanomedicine
V Leiro, S Duque Santos, CDF Lopes… - Advanced Functional …, 2018 - Wiley Online Library
Dendrimers have emerged as a powerful class of nanomaterials in the nanomedicine field
due to their unique structural features: globular, well‐defined, highly branched and …
due to their unique structural features: globular, well‐defined, highly branched and …