The red and the black

JD Simon, DN Peles - Accounts of chemical research, 2010 - ACS Publications
“Pigmentation, which is primarily determined by the amount, the type, and the distribution of
melanin, shows a remarkable diversity in human populations, and in this sense, it is an …

Functionality of epidermal melanin pigments: current knowledge on UV-dissipative mechanisms and research perspectives

A Huijser, A Pezzella, V Sundström - Physical chemistry chemical …, 2011 - pubs.rsc.org
So far it is not known whether epidermal melanins are solely photoprotective or also
phototoxic. Also largely unknown are underlying UV-induced mechanisms and impact of the …

Excited-state proton-transfer processes of DHICA resolved: From sub-picoseconds to nanoseconds

A Corani, A Pezzella, T Pascher… - The journal of …, 2013 - ACS Publications
Excited-state proton transfer has been hypothesized as a mechanism for UV energy
dissipation in eumelanin skin pigments. By using time-resolved fluorescence spectroscopy …

Vibrational characterization of pheomelanin and trichochrome F by Raman spectroscopy

I Galván, A Jorge, F Solano, K Wakamatsu - Spectrochimica Acta Part A …, 2013 - Elsevier
We characterize for the first time the vibrational state of natural pheomelanin using Raman
spectroscopy and model pigment synthesized from 5-S-cysteinyldopa. The shape of the …

Properties and functions of ocular melanins and melanosomes

M Rózanowska - Melanins and melanosomes: Biosynthesis …, 2011 - books.google.com
The color of human eyes is largely dependent on the amount, type, and distribution of
melanin present in the iris [1, 2]. However, the iris is not the only part of the uveal tract that …

Ultraviolet absorption coefficients of melanosomes containing eumelanin as related to the relative content of DHI and DHICA

DN Peles, E Lin, K Wakamatsu, S Ito… - The Journal of Physical …, 2010 - ACS Publications
Central to understanding the photochemical function (s) of melanosomes is the
determination of their absorption properties and an understanding of how the absorption …

Melanosome Origins, Diversity and Functional Relevance Across Animals

L D'Alba - Melanins: Functions, biotechnological production, and …, 2023 - Springer
Melanosomes are important organelles melanin is produced stored and mobilized
throughout animal tissues. Melanins confer unique properties to these organelles, including …

UV-absorption spectra of melanosomes containing varying 5, 6-dihydroxyindole and 5, 6-dihydroxyindole-2-carboxylic acid content

DN Peles, JD Simon - The Journal of Physical Chemistry B, 2011 - ACS Publications
Central to understanding the photochemical properties of melanosomes is a direct
measurement of their absorption coefficients. Herein, the absorption spectra of intact …

Skin too thin? The developing utility of zebrafish skin (neuro) pharmacology for CNS drug discovery research

M Nguyen, MK Poudel, AM Stewart, AV Kalueff - Brain research bulletin, 2013 - Elsevier
Skin coloration can be affected by many genetic, environmental and pharmacological
factors. Zebrafish (Danio rerio) are a useful and versatile model organism in biomedical …

The ultraviolet absorption coefficient of melanosomes decreases with increasing pheomelanin content

DN Peles, JD Simon - The Journal of Physical Chemistry B, 2010 - ACS Publications
Uveal melanosomes from the iridal stroma contain both eumelanin and pheomelanin, the
ratio of which varies with iris color. Herein, we report the absorption coefficient at λ= 244 nm …