Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy
B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
Mechanisms of multidrug resistance in cancer chemotherapy
K Bukowski, M Kciuk, R Kontek - International journal of molecular …, 2020 - mdpi.com
Cancer is one of the main causes of death worldwide. Despite the significant development of
methods of cancer healing during the past decades, chemotherapy still remains the main …
methods of cancer healing during the past decades, chemotherapy still remains the main …
The role of polyphenols in overcoming cancer drug resistance: A comprehensive review
P Maleki Dana, F Sadoughi, Z Asemi… - Cellular & molecular …, 2022 - Springer
Chemotherapeutic drugs are used to treat advanced stages of cancer or following surgery.
However, cancers often develop resistance against drugs, leading to failure of treatment and …
However, cancers often develop resistance against drugs, leading to failure of treatment and …
Differentiated Caco-2 cell models in food-intestine interaction study: Current applications and future trends
X Ding, X Hu, Y Chen, J Xie, M Ying, Y Wang… - Trends in Food Science & …, 2021 - Elsevier
Background Food-intestine interaction study has always been a hot topic in food science
and nutrition due to diverse physiological functions of intestine. Compared to expensive …
and nutrition due to diverse physiological functions of intestine. Compared to expensive …
Recent updates on mechanisms of resistance to 5-fluorouracil and reversal strategies in colon cancer treatment
S Azwar, HF Seow, M Abdullah, M Faisal Jabar… - Biology, 2021 - mdpi.com
Simple Summary Acquired resistance to chemotherapy by cancer cells is the predominant
factor in chemotherapy failure, which ultimately leads to disease progression and death …
factor in chemotherapy failure, which ultimately leads to disease progression and death …
Understanding and targeting resistance mechanisms in cancer
Resistance to cancer therapies has been a commonly observed phenomenon in clinical
practice, which is one of the major causes of treatment failure and poor patient survival. The …
practice, which is one of the major causes of treatment failure and poor patient survival. The …
New advances in the research of resistance to neoadjuvant chemotherapy in breast cancer
J An, C Peng, H Tang, X Liu, F Peng - International journal of molecular …, 2021 - mdpi.com
Breast cancer has an extremely high incidence in women, and its morbidity and mortality
rank first among female tumors. With the increasing development of medicine today, the …
rank first among female tumors. With the increasing development of medicine today, the …
Glutathione transferases: potential targets to overcome chemoresistance in solid tumors
M Pljesa-Ercegovac, A Savic-Radojevic… - International journal of …, 2018 - mdpi.com
Multifunctional enzymes glutathione transferases (GSTs) are involved in the development of
chemoresistance, thus representing a promising target for a novel approach in cancer …
chemoresistance, thus representing a promising target for a novel approach in cancer …
Drug-metabolizing enzymes: role in drug resistance in cancer
Although continuous researches are going on for the discovery of new chemotherapeutic
agents, resistance to these anticancer agents has made it really difficult to reach the fruitful …
agents, resistance to these anticancer agents has made it really difficult to reach the fruitful …
Bitter Melon (Momordica Charantia), a Nutraceutical Approach for Cancer Prevention and Therapy
Cancer is the second leading cause of death worldwide. Many dietary plant products show
promising anticancer effects. Bitter melon or bitter gourd (Momordica charantia) is a nutrient …
promising anticancer effects. Bitter melon or bitter gourd (Momordica charantia) is a nutrient …