Remarkable progress has been made in understanding the genetic basis of dilated
cardiomyopathy (DCM). Rare variants in> 30 genes, some also involved in other …

Dilated cardiomyopathy (DCM) is an umbrella term entailing a wide variety of genetic and
non-genetic etiologies, leading to left ventricular systolic dysfunction and dilatation, not …

ACMG SF v3.1 list for reporting of secondary findings in clinical exome and genome
sequencing: A policy statement of the American College of Medical Genetics and Genomics …

Aims Routine genetic testing in Dilated Cardiomyopathy (DCM) has recently become reality
using Next-Generation Sequencing. Several studies have explored the relationship between …

Troponin T (TnT) is a central player in the calcium regulation of actin thin filament function
and is essential for the contraction of striated muscles. Three homologous genes have …

A great deal of progress has recently been made in the discovery and understanding of the
genetics of familial dilated cardiomyopathy (FDC). A consensus has emerged that with a …

Background Diverse genetic backgrounds often lead to phenotypic heterogeneity in
cardiomyopathies (CMPs). Previous genotype-phenotype studies have primarily focused on …

Substantial progress has been made recently in understanding the genetic basis of
cardiomyopathy. Cardiomyopathies with known genetic cause include hypertrophic (HCM) …

Dilated cardiomyopathy (DCM), usually diagnosed as idiopathic dilated cardiomyopathy
(IDC), has been shown to have a familial basis in 20–35% of cases. Genetic studies in …

Inherited cardiomyopathies include hypertrophic cardiomyopathy, dilated cardiomyopathy,
arrhythmogenic right ventricular cardiomyopathy, left ventricular noncompaction, and …