Snake antivenom: Challenges and alternate approaches
Snake envenomation is still a serious threat to many countries in the world. The only
mainstay treatment depends on the administration of animal derived immunoglobulin based …
mainstay treatment depends on the administration of animal derived immunoglobulin based …
Plant-derived toxin inhibitors as potential candidates to complement antivenom treatment in snakebite envenomations
AAX Adrião, AO Dos Santos, EJSP de Lima… - Frontiers in …, 2022 - frontiersin.org
Snakebite envenomations (SBEs) are a neglected medical condition of global importance
that mainly affect the tropical and subtropical regions. Clinical manifestations include pain …
that mainly affect the tropical and subtropical regions. Clinical manifestations include pain …
Kaempferol from Moringa oleifera demonstrated potent antivenom activities via inhibition of metalloproteinase and attenuation of Bitis arietans venom–induced …
Bitis arietans venom (BAV) can induce severe pathophysiological disorders after
envenoming. However, studies have shown that the Moringa oleifera fraction is effective …
envenoming. However, studies have shown that the Moringa oleifera fraction is effective …
Naja naja snake venom-induced local toxicities in mice is by inflammasome activation
Snake bite envenomation causes tissue damage resulting in acute and chronic inflammatory
responses. Inflammasome activation is one of the factors involved in tissue damage in a …
responses. Inflammasome activation is one of the factors involved in tissue damage in a …
Phytochemical characterization and phospholipase A2 inhibitory effect of Vitex negundo L. root extracts
S Kusar, Z Saddiqe, MHHB Asad, F Ali… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Snake bites are a critical health issue in many parts of the
world particularly in Asian countries lacking efficient health facilities in rural areas. Cobra is …
world particularly in Asian countries lacking efficient health facilities in rural areas. Cobra is …
Revolutionizing snakebite care with novel antivenoms: Breakthroughs and barriers
Snakebite envenoming (SBE) is a global public health concern, primarily due to the lack of
effective antivenom for treating snakebites inflicted by medically significant venomous …
effective antivenom for treating snakebites inflicted by medically significant venomous …
Unraveling snake venom phospholipase A2: an overview of its structure, pharmacology, and inhibitors
GH Sampat, K Hiremath, J Dodakallanavar… - Pharmacological …, 2023 - Springer
Snake bite is a neglected disease that affects millions of people worldwide. WHO reported
approximately 5 million people are bitten by various species of snakes each year, resulting …
approximately 5 million people are bitten by various species of snakes each year, resulting …
Assessment of snakebite burdens, clinical features of envenomation, and strategies to improve snakebite management in Vietnam
A Patra, AK Mukherjee - Acta tropica, 2021 - Elsevier
The sheer paucity of scientific documentation of herpetofauna in Vietnam and the
rudimentary healthcare response to snakebite have stimulated this review. Over six decades …
rudimentary healthcare response to snakebite have stimulated this review. Over six decades …
Exploring the inhibitory potential of phytochemicals from Vernonia glaberrima leaves against snake venom toxins through computational simulation and experimental …
Abstract Phospholipase A 2 (PLA 2) is an enzyme present in appreciable quantity in snake
venoms which catalyze the hydrolysis of glycerophospholipids at sn-2 position and promote …
venoms which catalyze the hydrolysis of glycerophospholipids at sn-2 position and promote …
A First Look at the Inhibitory Potential of Urospatha sagittifolia (Araceae) Ethanolic Extract for Bothrops atrox Snakebite Envenomation
AL Vera-Palacios, JD Sacoto-Torres… - Toxins, 2022 - mdpi.com
Bothrops atrox snakebites are a relevant problem in the Amazon basin. In this biodiverse
region, the ethnomedicinal approach plays an important role as an alternative to antivenom …
region, the ethnomedicinal approach plays an important role as an alternative to antivenom …