Varicocele-mediated male infertility: from the perspective of testicular immunity and inflammation

Y Fang, Y Su, J Xu, Z Hu, K Zhao, C Liu… - Frontiers in …, 2021 - frontiersin.org
Background Varicocele (VC) is present in 35-40% of men with infertility. However, current
surgical and antioxidant treatments are not completely effective. In addition to oxidative …

[HTML][HTML] Urogenital infection as a risk factor for male infertility

HC Schuppe, A Pilatz, H Hossain… - Deutsches Ärzteblatt …, 2017 - ncbi.nlm.nih.gov
Background Infections of the genital tract are considered common causes of male fertility
disorders, with a prevalence of 6–10%. Most of the affected men are asymptomatic. The …

Relationship between varicocele and sperm DNA damage and the effect of varicocele repair: a meta-analysis

YJ Wang, RQ Zhang, YJ Lin, RG Zhang… - Reproductive biomedicine …, 2012 - Elsevier
Varicocele, a cause of male infertility, occurs in nearly 40% of infertile males. It has been
postulated that varicoceles may cause sperm DNA damage. Sperm DNA integrity has been …

Influence of reactive oxygen species on human sperm functions and fertilizing capacity including therapeutical approaches

S Chen, JP Allam, Y Duan, G Haidl - Archives of gynecology and obstetrics, 2013 - Springer
Background Reactive oxygen species (ROS) are an array of molecules including oxygen-
centered radicals, which are endowed with one or more unpaired electrons and non-radical …

[HTML][HTML] Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis

FTL Neto, M Roque, SC Esteves - Fertility and sterility, 2021 - Elsevier
Objective To evaluate the effect of varicocelectomy on sperm deoxyribonucleic acid
fragmentation (SDF) rates in infertile men with clinical varicocele. Design Systematic review …

[HTML][HTML] Are varicoceles associated with increased deoxyribonucleic acid fragmentation?

A Zini, G Dohle - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To perform a literature search on the association between varicocele and
sperm DNA fragmentation. DESIGN: Systematic review. PATIENT (S): Men with a varicocele …

Human testicular peritubular cells: more than meets the eye

A Mayerhofer - Reproduction, 2013 - rep.bioscientifica.com
In healthy men, several layers of inconspicuously flat cells and extracellular matrix (ECM)
proteins build the wall of the seminiferous tubules. The cells of this wall, peritubular cells, are …

Alpha-lipoic acid improves sperm motility in infertile men after varicocelectomy: a triple-blind randomized controlled trial

B Abbasi, N Molavi, M Tavalaee, H Abbasi… - Reproductive …, 2020 - Elsevier
Research question Does supplementation with alpha-lipoic acid (ALA) enhance sperm
parameters and/or the status of sperm lipid peroxidation and DNA fragmentation in men who …

An update on the role of medical treatment including antioxidant therapy in varicocele

H Garg, R Kumar - Asian journal of andrology, 2016 - journals.lww.com
Varicocele-associated male infertility has classically been managed using surgery or
assisted reproductive techniques. With increasing evidence of oxidative stress as a …

Mast cells: an expanding pathophysiological role from allergy to other disorders

P Anand, B Singh, AS Jaggi, N Singh - Naunyn-Schmiedeberg's archives …, 2012 - Springer
The mast cells are multi-effector cells with wide distribution in the different body parts and
traditionally their role has been well-defined in the development of IgE-mediated …