Neuronal XBP-1 activates intestinal lysosomes to improve proteostasis in C. elegans
The unfolded protein response of the endoplasmic reticulum (UPR ER) is a crucial mediator
of secretory pathway homeostasis. Expression of the spliced and active form of the UPR ER …
of secretory pathway homeostasis. Expression of the spliced and active form of the UPR ER …
Mitochondrial Activity and Cyr1 Are Key Regulators of Ras1 Activation of C. albicans Virulence Pathways
N Grahl, EG Demers, AK Lindsay, CE Harty… - PLoS …, 2015 - journals.plos.org
Candida albicans is both a major fungal pathogen and a member of the commensal human
microflora. The morphological switch from yeast to hyphal growth is associated with disease …
microflora. The morphological switch from yeast to hyphal growth is associated with disease …
Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide
The antibiotic pyrazinamide (PZA) is a cornerstone of tuberculosis (TB) therapy that shortens
treatment durations by several months despite being only weakly bactericidal. Intriguingly …
treatment durations by several months despite being only weakly bactericidal. Intriguingly …
Enhanced mitochondrial membrane potential and ATP synthesis by photobiomodulation increases viability of the auditory cell line after gentamicin-induced intrinsic …
Photobiomodulation (PBM) has been suggested to have a therapeutic effect on irreversible
hearing loss induced by aminoglycosides, including gentamicin (GM). However, its …
hearing loss induced by aminoglycosides, including gentamicin (GM). However, its …
Fed-batch mixotrophic cultivation of Chlamydomonas reinhardtii for high-density cultures
FJ Fields, JT Ostrand, SP Mayfield - Algal Research, 2018 - Elsevier
The green algae Chlamydomonas reinhardtii is a model organism that has been proposed
as a potential production platform for high-value recombinant products, but to date, there has …
as a potential production platform for high-value recombinant products, but to date, there has …
Delineation of cell death mechanisms induced by synergistic effects of statins and erlotinib in non-small cell lung cancer cell (NSCLC) lines
A Otahal, D Aydemir, E Tomasich, C Minichsdorfer - Scientific Reports, 2020 - nature.com
Abstract Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) have
been shown to overcome tyrosine kinase inhibitor (TKI) resistance in epithelial growth factor …
been shown to overcome tyrosine kinase inhibitor (TKI) resistance in epithelial growth factor …
Dispersive liquid-liquid microextraction coupled with digital image colorimetric analysis for detection of total iron in water and food samples
B Peng, G Chen, K Li, M Zhou, J Zhang, S Zhao - Food chemistry, 2017 - Elsevier
A simple and low cost assay for total iron in various samples based on dispersive liquid-
liquid microextraction (DLLME) coupled with digital scanning image analysis was proposed …
liquid microextraction (DLLME) coupled with digital scanning image analysis was proposed …
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity
Non-alcoholic fatty liver disease (NAFLD) represents a key feature of obesity-related type 2
diabetes with increasing prevalence worldwide. To our knowledge, no treatment options are …
diabetes with increasing prevalence worldwide. To our knowledge, no treatment options are …
Constituents of neutrophil extracellular traps induce in vitro collagen formation in mare endometrium
MR Rebordão, A Amaral, K Lukasik… - Theriogenology, 2018 - Elsevier
Neutrophil extracellular traps (NETs) are DNA complexes carrying nuclear and cytoplasmic
proteins, such as elastase (ELA), cathepsin-G (CAT) and myeloperoxidase (MPO). Mare …
proteins, such as elastase (ELA), cathepsin-G (CAT) and myeloperoxidase (MPO). Mare …
Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrations
As human embryonic stem cells (hESCs) steadily progress towards regenerative medicine
applications there is an increasing emphasis on the development of bioreactor platforms that …
applications there is an increasing emphasis on the development of bioreactor platforms that …