[HTML][HTML] Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures
This work aimed to develop and produce lacosamide-loaded niosomes coated with chitosan
(LCA-CTS-NSM) using a thin-film hydration method and the Box-Behnken design. The effect …
(LCA-CTS-NSM) using a thin-film hydration method and the Box-Behnken design. The effect …
[HTML][HTML] Nose to brain strategy coupled to nano vesicular system for natural products delivery: Focus on synaptic plasticity in Alzheimer's disease
N Maisto, D Mango - Journal of Pharmaceutical Analysis, 2024 - Elsevier
A wide number of natural molecules demonstrated neuroprotective effects on synaptic
plasticity defects induced by amyloid-β (Aβ) in ex vivo and in vivo Alzheimer's disease (AD) …
plasticity defects induced by amyloid-β (Aβ) in ex vivo and in vivo Alzheimer's disease (AD) …
Comparative Serum and Brain Pharmacokinetics of Quercetin after Oral and Nasal Administration to Rats as Lyophilized Complexes with β-Cyclodextrin Derivatives …
K Manta, P Papakyriakopoulou, A Nikolidaki, E Balafas… - Pharmaceutics, 2023 - mdpi.com
Quercetin (Que) is one of the most studied flavonoids with strong antioxidant properties
ascribed to its ability to bind free radicals and inactivate them. However, the low solubility of …
ascribed to its ability to bind free radicals and inactivate them. However, the low solubility of …
Transferosome-Based Intranasal Drug Delivery Systems for the Management of Schizophrenia: a Futuristic Approach
Schizophrenia is serious and prevalent psychotic condition in which patients misinterpret the
real conditions and might cause combination of symptoms like hallucinations, delusions …
real conditions and might cause combination of symptoms like hallucinations, delusions …
A Novel Chitosan-coated Leciplex Loaded with Ambrisentan as a Possible Pulmonary Nanosystem: Optimization, Characterization, and Pharmacokinetics …
The purpose of this research was to formulate, optimize, and characterize ambrisentan
chitosan-coated LeciPlex (AMS-CTS-LPX) to increase the therapeutic effectiveness and …
chitosan-coated LeciPlex (AMS-CTS-LPX) to increase the therapeutic effectiveness and …
[HTML][HTML] Behavioral and neuropathological features of Alzheimer's disease are attenuated in 5xFAD mice treated with intranasal GHK peptide
M Tucker, GY Liao, JY Park, M Rosenfeld, J Wezeman… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Efforts to find disease modifying treatments for Alzheimer's disease (AD) have met with
limited success in part because the focus has been on testing drugs that target a specific …
limited success in part because the focus has been on testing drugs that target a specific …
Intranasal nanotransferosomal gel for quercetin brain targeting: II. Antidepressant effect in an experimental animal model
Depression is a serious mental disorder and the most prevalent cause of disability and
suicide worldwide. Quercetin (QER) demonstrated antidepressant effects in rats exhibiting …
suicide worldwide. Quercetin (QER) demonstrated antidepressant effects in rats exhibiting …
[引用][C] Assessing the Socio‐Demographic Factors Associated with Viral Conjunctivitis: A Cross‐Sectional Survey
S Kosamia - Res. J. Med. Sci, 2023