Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?
CL Kuo, A Ponneri Babuharisankar, YC Lin… - Journal of biomedical …, 2022 - Springer
The major concept of" oxidative stress" is an excess elevated level of reactive oxygen
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …
Oxidative stress-induced endothelial dysfunction in cardiovascular diseases
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …
understanding of the mechanisms underlying CVD is key for better management or …
The impact of HIV-and ART-induced mitochondrial dysfunction in cellular senescence and aging
M Schank, J Zhao, JP Moorman, ZQ Yao - Cells, 2021 - mdpi.com
According to the WHO, 38 million individuals were living with human immunodeficiency virus
(HIV), 25.4 million of which were using antiretroviral therapy (ART) at the end of 2019 …
(HIV), 25.4 million of which were using antiretroviral therapy (ART) at the end of 2019 …
The pathophysiological role of mitochondrial oxidative stress in lung diseases
X Liu, Z Chen - Journal of Translational Medicine, 2017 - Springer
Mitochondria are critically involved in reactive oxygen species (ROS)-dependent lung
diseases, such as lung fibrosis, asbestos, chronic airway diseases and lung cancer …
diseases, such as lung fibrosis, asbestos, chronic airway diseases and lung cancer …
Multifunctional Iridium (III)–Platinum (IV) Conjugates as Potent Anticancer Theranostic Agents
A Gupta, AK Pandey, T Mondal… - Journal of Medicinal …, 2023 - ACS Publications
In this article, we report IriPlatins 1–3, a new class of heterobimetallic Ir (III)-Pt (IV)
conjugates as multifunctional potent anticancer theranostic agents. In the designed …
conjugates as multifunctional potent anticancer theranostic agents. In the designed …
NNRTI and liver damage: evidence of their association and the mechanisms involved
AM Benedicto, I Fuster-Martínez, J Tosca… - Cells, 2021 - mdpi.com
Due to the improved effectiveness and safety of combined antiretroviral therapy, human
immunodeficiency virus (HIV) infection has become a manageable, chronic condition rather …
immunodeficiency virus (HIV) infection has become a manageable, chronic condition rather …
A critical review of the biochemical mechanisms and epigenetic modifications in HIV-and antiretroviral-induced metabolic syndrome
Metabolic syndrome (MetS) is a non-communicable disease characterised by a cluster of
metabolic irregularities. Alarmingly, the prevalence of MetS in people living with Human …
metabolic irregularities. Alarmingly, the prevalence of MetS in people living with Human …
Cell toxicity mechanism and biomarker
Y Zhang - Clinical and translational medicine, 2018 - Springer
Cell toxicity may result in organ dysfunction and cause severe health problem. Recent
studies revealed many toxicants may induced the over production of Nitric oxide, reactive …
studies revealed many toxicants may induced the over production of Nitric oxide, reactive …
Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer
L Fu, A Yonemura, N Yasuda-Yoshihara, T Umemoto… - Gastric Cancer, 2022 - Springer
Background Signet ring cell carcinoma (SRCC) is a particular histologic variant of gastric
cancer (GC). However, the critical factor related to the aggressive characteristics of SRCC …
cancer (GC). However, the critical factor related to the aggressive characteristics of SRCC …
Mitochondria in health and disease
Mitochondrial biology has become an area of intense research owing to the unique
physiology of the organelle and its role in several types of cancers and other disorders. It …
physiology of the organelle and its role in several types of cancers and other disorders. It …